GPSM3 and C11orf45

Data Source:
BioGRID (two hybrid)

		GPSM3	C11orf45
Description		G protein signaling modulator 3	chromosome 11 open reading frame 45
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cellular_component Cytoplasm Plasma Membrane	Extracellular Region
	Molecular Function	Molecular_function Protein Binding GTPase Regulator Activity	Protein Binding
	Biological Process	Positive Regulation Of Leukocyte Chemotaxis Biological_process Positive Regulation Of Inflammatory Response Regulation Of Catalytic Activity Positive Regulation Of Cytokine Production Involved In Inflammatory Response
Pathways		G alpha (i) signalling events
Drugs
Diseases
GWAS		Asthma ( 31619474) Atopic dermatitis ( 23042114 25574825) Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 31043756) Blood protein levels ( 28240269) Body mass index ( 31453325) Body mass index variance ( 31453325) Estimated glomerular filtration rate ( 31152163) Hip circumference ( 31453325) Hip circumference variance ( 31453325) Inflammatory bowel disease ( 28067908) Obesity-related traits ( 23251661) Prostate cancer ( 23535732) Sarcoidosis (non-Lofgren's syndrome without extrapulmonary manifestations) ( 26651848) Ulcerative colitis ( 28067908)	Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Resting heart rate ( 27798624)
Interacting Genes		45 interacting genes: ACMSD ANKRD33 ASB15 BATF2 BMF C10orf82 C11orf45 C9orf57 CHRDL2 COA7 CTAG1A CTAG1B FAM86C1P FGFR3 GATAD2B GNAI1 GNAI2 GNAI3 HELT HIGD2B HRAS HSF2BP IQCE IVD KRTAP11-1 KRTAP13-3 KRTAP19-4 MAPK7 MBD3L1 MEOX2 NR0B2 P4HA3 PRR5 RIPK4 RSPO4 SPAG8 SPRY3 STXBP5L TADA2A TEX11 UFSP1 USHBP1 YWHAZ ZNF20 ZNF581	7 interacting genes: APP EFHC1 FBXO44 FRS3 GPSM3 PLEKHF2 TLX3
Entrez ID		63940	219833
HPRD ID		13605	11344
Ensembl ID		ENSG00000213654	ENSG00000174370
Uniprot IDs		A0A024RCP6 Q9Y4H4	A0A024R3N7 Q8TAV5
PDB IDs
Enriched GO Terms of Interacting Partners?
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