GPSM3 and ACMSD

Data Source:
BioGRID (two hybrid)

		GPSM3	ACMSD
Description		G protein signaling modulator 3	aminocarboxymuconate semialdehyde decarboxylase
Image		No pdb structure
GO Annotations	Cellular Component	Cellular_component Cytoplasm Plasma Membrane	Cytoplasm Cytosol
	Molecular Function	Molecular_function Protein Binding GTPase Regulator Activity	Aminocarboxymuconate-semialdehyde Decarboxylase Activity Protein Binding Zinc Ion Binding Hydrolase Activity Carboxy-lyase Activity
	Biological Process	Positive Regulation Of Leukocyte Chemotaxis Biological_process Positive Regulation Of Inflammatory Response Regulation Of Catalytic Activity Positive Regulation Of Cytokine Production Involved In Inflammatory Response	Tryptophan Catabolic Process Secondary Metabolic Process Negative Regulation Of Quinolinate Biosynthetic Process Picolinic Acid Biosynthetic Process Regulation Of 'de Novo' NAD Biosynthetic Process From Tryptophan
Pathways		G alpha (i) signalling events	Tryptophan catabolism
Drugs
Diseases
GWAS		Asthma ( 31619474) Atopic dermatitis ( 23042114 25574825) Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 31043756) Blood protein levels ( 28240269) Body mass index ( 31453325) Body mass index variance ( 31453325) Estimated glomerular filtration rate ( 31152163) Hip circumference ( 31453325) Hip circumference variance ( 31453325) Inflammatory bowel disease ( 28067908) Obesity-related traits ( 23251661) Prostate cancer ( 23535732) Sarcoidosis (non-Lofgren's syndrome without extrapulmonary manifestations) ( 26651848) Ulcerative colitis ( 28067908)	Apolipoprotein B levels ( 32203549) Blood metabolite levels ( 24816252) Body mass index ( 26426971) Diisocyanate-induced asthma ( 25918132) Free thyroxine concentration ( 30367059) Hand grip strength ( 29691431) Hematocrit ( 28017375) LDL cholesterol levels ( 32203549) Obesity-related traits ( 23251661) Parkinson's disease ( 21292315 25064009) Red blood cell count ( 32888494)
Interacting Genes		45 interacting genes: ACMSD ANKRD33 ASB15 BATF2 BMF C10orf82 C11orf45 C9orf57 CHRDL2 COA7 CTAG1A CTAG1B FAM86C1P FGFR3 GATAD2B GNAI1 GNAI2 GNAI3 HELT HIGD2B HRAS HSF2BP IQCE IVD KRTAP11-1 KRTAP13-3 KRTAP19-4 MAPK7 MBD3L1 MEOX2 NR0B2 P4HA3 PRR5 RIPK4 RSPO4 SPAG8 SPRY3 STXBP5L TADA2A TEX11 UFSP1 USHBP1 YWHAZ ZNF20 ZNF581	3 interacting genes: GPSM3 MAGEA11 USHBP1
Entrez ID		63940	130013
HPRD ID		13605	12326
Ensembl ID		ENSG00000213654	ENSG00000153086
Uniprot IDs		A0A024RCP6 Q9Y4H4	A0A0S2Z681 Q6ZV40 Q8TDX5
PDB IDs			2WM1 4IGM 4IGN 4IH3 4OFC
Enriched GO Terms of Interacting Partners?
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