SH2D4A and GRAMD4

Data Source:
BioGRID (two hybrid)

		SH2D4A	GRAMD4
Description		SH2 domain containing 4A	GRAM domain containing 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol	Mitochondrion Endoplasmic Reticulum Membrane Integral Component Of Membrane Mitochondrial Membrane
	Molecular Function	Protein Binding Phosphatase Binding	Molecular_function Protein Binding
	Biological Process	Negative Regulation Of Phosphatase Activity	Apoptotic Process Negative Regulation Of Toll-like Receptor 9 Signaling Pathway Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Pathways
Drugs
Diseases
GWAS		Smooth-surface caries ( 24556642) Urate levels in overweight individuals ( 25811787) Urinary albumin excretion rate in type 1 diabetes ( 24595857)	Urate levels in obese individuals ( 25811787)
Interacting Genes		74 interacting genes: ALAS1 ARC BLOC1S2 CADPS CASK CCDC172 CCDC88B CDR2 CDR2L CEP70 CEP76 CFAP53 DBNL FCHO1 FCHSD2 FSD2 GOLGA2 GOLGA6L9 GPRASP2 GRAMD4 GRAP2 GRB2 HCLS1 HMBOX1 HOOK2 HSF2BP IKZF1 KRT40 LDOC1 LZTS2 MAGEA11 MAGEA6 MBD3L1 MEOX2 MORN3 MRFAP1 MTUS2 NECAB2 NINL NUTM1 OLIG1 PDE4DIP PICK1 PLEKHG4 PNMA1 PPP1CB PRKAR1B PSTPIP1 RINT1 SH3GL1 SH3RF1 SKAP1 SORBS2 SORBS3 SPAG5 STAM2 STX11 TACC1 TFIP11 TRAF2 TRIM23 TRIM27 TRIML2 TTC19 UBXN11 USHBP1 VPS52 WWOX YPEL2 YPEL3 ZBTB16 ZMYND12 ZNF655 ZNF774	13 interacting genes: APP C2CD6 CCDC146 EXOC8 FAM9B GADD45G MTMR9 NTAQ1 PLEKHF2 RBL2 SH2D4A SMARCD1 TACC2
Entrez ID		63898	23151
HPRD ID		08340	11107
Ensembl ID		ENSG00000104611	ENSG00000075240
Uniprot IDs		Q9H788	Q6IC98
PDB IDs
Enriched GO Terms of Interacting Partners?
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