GRAMD4 and SH2D4A

Data Source:
BioGRID (two hybrid)

		GRAMD4	SH2D4A
Description		GRAM domain containing 4	SH2 domain containing 4A
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Mitochondrion Endoplasmic Reticulum Membrane Integral Component Of Membrane Mitochondrial Membrane	Cytoplasm Cytosol
	Molecular Function	Molecular_function Protein Binding	Protein Binding Phosphatase Binding
	Biological Process	Apoptotic Process Negative Regulation Of Toll-like Receptor 9 Signaling Pathway Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process	Negative Regulation Of Phosphatase Activity
Pathways
Drugs
Diseases
GWAS		Urate levels in obese individuals ( 25811787)	Smooth-surface caries ( 24556642) Urate levels in overweight individuals ( 25811787) Urinary albumin excretion rate in type 1 diabetes ( 24595857)
Interacting Genes		13 interacting genes: APP C2CD6 CCDC146 EXOC8 FAM9B GADD45G MTMR9 NTAQ1 PLEKHF2 RBL2 SH2D4A SMARCD1 TACC2	74 interacting genes: ALAS1 ARC BLOC1S2 CADPS CASK CCDC172 CCDC88B CDR2 CDR2L CEP70 CEP76 CFAP53 DBNL FCHO1 FCHSD2 FSD2 GOLGA2 GOLGA6L9 GPRASP2 GRAMD4 GRAP2 GRB2 HCLS1 HMBOX1 HOOK2 HSF2BP IKZF1 KRT40 LDOC1 LZTS2 MAGEA11 MAGEA6 MBD3L1 MEOX2 MORN3 MRFAP1 MTUS2 NECAB2 NINL NUTM1 OLIG1 PDE4DIP PICK1 PLEKHG4 PNMA1 PPP1CB PRKAR1B PSTPIP1 RINT1 SH3GL1 SH3RF1 SKAP1 SORBS2 SORBS3 SPAG5 STAM2 STX11 TACC1 TFIP11 TRAF2 TRIM23 TRIM27 TRIML2 TTC19 UBXN11 USHBP1 VPS52 WWOX YPEL2 YPEL3 ZBTB16 ZMYND12 ZNF655 ZNF774
Entrez ID		23151	63898
HPRD ID		11107	08340
Ensembl ID		ENSG00000075240	ENSG00000104611
Uniprot IDs		Q6IC98	Q9H788
PDB IDs
Enriched GO Terms of Interacting Partners?
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