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CXCL11 and CCL8
Data Source:
BioGRID
(pull down)
CXCL11
CCL8
Description
C-X-C motif chemokine ligand 11
C-C motif chemokine ligand 8
Image
GO Annotations
Cellular Component
Extracellular Region
Extracellular Space
Extracellular Space
Molecular Function
Protein Binding
Chemokine Activity
Heparin Binding
CXCR Chemokine Receptor Binding
CXCR3 Chemokine Receptor Binding
Protein Kinase Activity
Protein Binding
Chemokine Activity
Heparin Binding
Phospholipase Activator Activity
CCR Chemokine Receptor Binding
Biological Process
Chemotaxis
Inflammatory Response
Signal Transduction
G Protein-coupled Receptor Signaling Pathway
Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway
Cell-cell Signaling
T Cell Chemotaxis
Neutrophil Chemotaxis
Regulation Of Cell Population Proliferation
Positive Regulation Of Release Of Sequestered Calcium Ion Into Cytosol
Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide
Chemokine-mediated Signaling Pathway
Cellular Response To Lipopolysaccharide
Monocyte Chemotaxis
Positive Regulation Of Leukocyte Migration
Protein Phosphorylation
Calcium Ion Transport
Cellular Calcium Ion Homeostasis
Exocytosis
Chemotaxis
Inflammatory Response
Signal Transduction
G Protein-coupled Receptor Signaling Pathway
Cell-cell Signaling
Response To Virus
Neutrophil Chemotaxis
Positive Regulation Of GTPase Activity
Negative Regulation By Host Of Viral Genome Replication
Eosinophil Chemotaxis
Lymphocyte Chemotaxis
Chemokine-mediated Signaling Pathway
Positive Regulation Of ERK1 And ERK2 Cascade
Negative Regulation Of Leukocyte Proliferation
Cellular Response To Interferon-gamma
Cellular Response To Interleukin-1
Cellular Response To Tumor Necrosis Factor
Pathways
Chemokine receptors bind chemokines
G alpha (i) signalling events
Drugs
Pidolic acid
Diseases
GWAS
Blood protein levels (
30072576
29875488
28240269
)
Hippocampal volume (
29274321
)
Neonatal cytokine/chemokine levels (fetal genetic effect) (
30134952
)
Blood protein levels (
30072576
29875488
28240269
)
Crohn's disease (
22412388
)
Interacting Genes
25 interacting genes:
CCL1
CCL11
CCL13
CCL20
CCL21
CCL24
CCL25
CCL26
CCL5
CCL8
CCR3
CXCL10
CXCL12
CXCL14
CXCL2
CXCL9
CXCR3
DPP4
LRRK2
MTUS2
PF4
PF4V1
PPBP
SMARCB1
XCL1
20 interacting genes:
ACKR1
ACKR2
ACKR4
CCL11
CCL13
CCL2
CCL26
CCR1
CCR3
CCR5
CXCL10
CXCL11
CXCL17
CXCL2
CXCL6
CXCL8
MMP3
PPBP
VCAN
XCL2
Entrez ID
6373
6355
HPRD ID
05329
03791
Ensembl ID
ENSG00000169248
ENSG00000108700
Uniprot IDs
O14625
P80075
PDB IDs
1RJT
1ESR
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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