CXCL11 and PF4V1

Data Source:
BioGRID (pull down, pull down)

		CXCL11	PF4V1
Description		C-X-C motif chemokine ligand 11	platelet factor 4 variant 1
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GO Annotations	Cellular Component	Extracellular Region Extracellular Space	Extracellular Space
	Molecular Function	Protein Binding Chemokine Activity Heparin Binding CXCR Chemokine Receptor Binding CXCR3 Chemokine Receptor Binding	Protein Binding Chemokine Activity Heparin Binding CXCR Chemokine Receptor Binding
	Biological Process	Chemotaxis Inflammatory Response Signal Transduction G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Cell-cell Signaling T Cell Chemotaxis Neutrophil Chemotaxis Regulation Of Cell Population Proliferation Positive Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Chemokine-mediated Signaling Pathway Cellular Response To Lipopolysaccharide	Inflammatory Response Platelet Activation Neutrophil Chemotaxis Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Chemokine-mediated Signaling Pathway Cellular Response To Lipopolysaccharide
Pathways		Chemokine receptors bind chemokines G alpha (i) signalling events	Common Pathway of Fibrin Clot Formation Cell surface interactions at the vascular wall
Drugs
Diseases
GWAS		Blood protein levels ( 30072576 29875488 28240269) Hippocampal volume ( 29274321) Neonatal cytokine/chemokine levels (fetal genetic effect) ( 30134952)	Blood protein levels ( 29875488) Inflammatory bowel disease ( 23128233)
Interacting Genes		25 interacting genes: CCL1 CCL11 CCL13 CCL20 CCL21 CCL24 CCL25 CCL26 CCL5 CCL8 CCR3 CXCL10 CXCL12 CXCL14 CXCL2 CXCL9 CXCR3 DPP4 LRRK2 MTUS2 PF4 PF4V1 PPBP SMARCB1 XCL1	15 interacting genes: CCL11 CCL19 CCL21 CCL22 CCL25 CCL26 CCL27 CCL28 CCL4L1 CXCL10 CXCL11 CXCL12 CXCL13 XCL1 XCL2
Entrez ID		6373	5197
HPRD ID		05329	01427
Ensembl ID		ENSG00000169248	ENSG00000109272
Uniprot IDs		O14625	P10720
PDB IDs		1RJT	4HSV
Enriched GO Terms of Interacting Partners?
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