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CCL8

Description C-C motif chemokine ligand 8
Image
GO Annotations Cellular Component
  • Extracellular Space
Molecular Function
  • Protein Kinase Activity
  • Protein Binding
  • Chemokine Activity
  • Heparin Binding
  • Phospholipase Activator Activity
  • CCR Chemokine Receptor Binding
Biological Process
  • Monocyte Chemotaxis
  • Positive Regulation Of Leukocyte Migration
  • Protein Phosphorylation
  • Calcium Ion Transport
  • Cellular Calcium Ion Homeostasis
  • Exocytosis
  • Chemotaxis
  • Inflammatory Response
  • Signal Transduction
  • G Protein-coupled Receptor Signaling Pathway
  • Cell-cell Signaling
  • Response To Virus
  • Neutrophil Chemotaxis
  • Positive Regulation Of GTPase Activity
  • Negative Regulation By Host Of Viral Genome Replication
  • Eosinophil Chemotaxis
  • Lymphocyte Chemotaxis
  • Chemokine-mediated Signaling Pathway
  • Positive Regulation Of ERK1 And ERK2 Cascade
  • Negative Regulation Of Leukocyte Proliferation
  • Cellular Response To Interferon-gamma
  • Cellular Response To Interleukin-1
  • Cellular Response To Tumor Necrosis Factor
Pathways
Drugs
  • Pidolic acid
Diseases
GWAS
  • Blood protein levels ( 30072576 29875488 28240269)
  • Crohn's disease ( 22412388)
Novel Interacting Genes 1 novel interacting genes: SDF2
Interacting Genes 20 interacting genes: ACKR1 ACKR2 ACKR4 CCL11 CCL13 CCL2 CCL26 CCR1 CCR3 CCR5 CXCL10 CXCL11 CXCL17 CXCL2 CXCL6 CXCL8 MMP3 PPBP VCAN XCL2
Entrez ID 6355
HPRD ID 03791
Ensembl ID ENSG00000108700
Uniprot IDs P80075
PDB IDs 1ESR
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025