CCL1 and CXCL11

Data Source:
BioGRID (pull down)

		CCL1	CXCL11
Description		C-C motif chemokine ligand 1	C-X-C motif chemokine ligand 11
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GO Annotations	Cellular Component	Extracellular Region Extracellular Space	Extracellular Region Extracellular Space
	Molecular Function	Chemokine Activity CCR Chemokine Receptor Binding	Protein Binding Chemokine Activity Heparin Binding CXCR Chemokine Receptor Binding CXCR3 Chemokine Receptor Binding
	Biological Process	Monocyte Chemotaxis Cellular Calcium Ion Homeostasis Chemotaxis Inflammatory Response Signal Transduction G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Viral Process Neutrophil Chemotaxis Positive Regulation Of Interleukin-17 Production Positive Regulation Of GTPase Activity Eosinophil Chemotaxis Lymphocyte Chemotaxis Positive Regulation Of Inflammatory Response Chemokine-mediated Signaling Pathway Positive Regulation Of ERK1 And ERK2 Cascade Cellular Response To Interferon-gamma Cellular Response To Interleukin-1 Cellular Response To Tumor Necrosis Factor Positive Regulation Of Monocyte Chemotaxis	Chemotaxis Inflammatory Response Signal Transduction G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Cell-cell Signaling T Cell Chemotaxis Neutrophil Chemotaxis Regulation Of Cell Population Proliferation Positive Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Chemokine-mediated Signaling Pathway Cellular Response To Lipopolysaccharide
Pathways		Chemokine receptors bind chemokines G alpha (i) signalling events	Chemokine receptors bind chemokines G alpha (i) signalling events
Drugs
Diseases
GWAS		Crohn's disease ( 22412388)	Blood protein levels ( 30072576 29875488 28240269) Hippocampal volume ( 29274321) Neonatal cytokine/chemokine levels (fetal genetic effect) ( 30134952)
Interacting Genes		3 interacting genes: CCR8 CXCL11 HUWE1	25 interacting genes: CCL1 CCL11 CCL13 CCL20 CCL21 CCL24 CCL25 CCL26 CCL5 CCL8 CCR3 CXCL10 CXCL12 CXCL14 CXCL2 CXCL9 CXCR3 DPP4 LRRK2 MTUS2 PF4 PF4V1 PPBP SMARCB1 XCL1
Entrez ID		6346	6373
HPRD ID		01654	05329
Ensembl ID		ENSG00000108702	ENSG00000169248
Uniprot IDs		P22362	O14625
PDB IDs		1EL0 4OIJ 4OIK	1RJT
Enriched GO Terms of Interacting Partners?
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