SCD and TMEM30B

Data Source:
BioGRID (two hybrid)

		SCD	TMEM30B
Description		stearoyl-CoA desaturase	transmembrane protein 30B
Image			No pdb structure
GO Annotations	Cellular Component	Nucleolus Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane Integral Component Of Endoplasmic Reticulum Membrane	Endoplasmic Reticulum Golgi Apparatus Plasma Membrane Integral Component Of Membrane
	Molecular Function	Stearoyl-CoA 9-desaturase Activity Iron Ion Binding Protein Binding Oxidoreductase Activity Palmitoyl-CoA 9-desaturase Activity	Protein Binding Aminophospholipid Flippase Activity
	Biological Process	Unsaturated Fatty Acid Biosynthetic Process Regulation Of Cholesterol Biosynthetic Process Fatty-acyl-CoA Biosynthetic Process Response To Fatty Acid Positive Regulation Of Cold-induced Thermogenesis Monounsaturated Fatty Acid Biosynthetic Process	Aminophospholipid Transport Phospholipid Translocation Positive Regulation Of Protein Exit From Endoplasmic Reticulum Aminophospholipid Translocation
Pathways		Activation of gene expression by SREBF (SREBP) Fatty acyl-CoA biosynthesis NR1H2 & NR1H3 regulate gene expression linked to lipogenesis
Drugs
Diseases
GWAS		Blood metabolite levels ( 24816252) Blood metabolite ratios ( 24816252) Glycerophospholipid levels ( 26068415) Macular thickness ( 30535121) Metabolic traits ( 21886157) Metabolite levels ( 23823483) Palmitic acid (16:0) levels ( 23362303) Palmitoleic acid (16:1n-7) levels ( 23362303) Vaccenic acid (18:1n-7) levels ( 28298293) White blood cell count (basophil) ( 27863252)	Nickel levels ( 26025379) Obesity-related traits ( 23251661) Venous thromboembolism adjusted for sickle cell variant rs77121243-T ( 28203683)
Interacting Genes		41 interacting genes: APP AQP6 CD207 CD33 CERS4 CLEC12B CREB3L1 CYB561 CYB5A CYBC1 ERGIC3 GJB1 GPR152 GPR42 GPX8 HSD17B13 JAGN1 KCNJ6 MARCHF5 MCFD2 MFSD14B MGST3 MTIF3 NEDD4L PVR REEP2 RETREG3 RNF5 SCN3B SEC11C SLC10A6 SLC7A14 SPAG4 STOM TIMMDC1 TLCD4 TMEM30B TMPRSS2 TMX2 UBC VMA21	4 interacting genes: GPR42 PMP22 SCD SFTPC
Entrez ID		6319	161291
HPRD ID		04941	18567
Ensembl ID		ENSG00000099194	ENSG00000182107
Uniprot IDs		O00767	Q3MIR4
PDB IDs		4ZYO
Enriched GO Terms of Interacting Partners?
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