SBF1 and CYB5R3

Data Source:
BioGRID (affinity chromatography technology)

		SBF1	CYB5R3
Description		SET binding factor 1	cytochrome b5 reductase 3
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Endoplasmic Reticulum Membrane Cytosol Membrane Integral Component Of Membrane Nuclear Body Perinuclear Region Of Cytoplasm	Extracellular Region Cytoplasm Mitochondrion Mitochondrial Outer Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Lipid Droplet Hemoglobin Complex Membrane Azurophil Granule Lumen Nitric-oxide Synthase Complex
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity Protein Tyrosine/serine/threonine Phosphatase Activity Phosphatase Activity Phosphatase Regulator Activity	Cytochrome-b5 Reductase Activity, Acting On NAD(P)H Protein Binding AMP Binding ADP Binding Nitrite Reductase (NO-forming) Activity NAD Binding FAD Binding
	Biological Process	Protein Dephosphorylation Phosphatidylinositol Biosynthetic Process Spermatogenesis Regulation Of GTPase Activity	Cholesterol Biosynthetic Process Xenobiotic Metabolic Process Nitric Oxide Biosynthetic Process Blood Circulation L-ascorbic Acid Metabolic Process Neutrophil Degranulation
Pathways		Synthesis of PIPs at the ER membrane RAB GEFs exchange GTP for GDP on RABs	Vitamin C (ascorbate) metabolism Phase I - Functionalization of compounds Neutrophil degranulation
Drugs			NADH Flavin adenine dinucleotide Copper
Diseases			Methemoglobinemia
GWAS			Initial pursuit acceleration ( 29064472)
Interacting Genes		7 interacting genes: AATK HSPB1 KMT2A MTMR2 PDPK1 SUV39H1 TNFSF11	61 interacting genes: ADAM33 AGTRAP AIG1 ALG8 AQP6 ASGR1 BNIP2 CDIPT CERS4 CNIH1 COL8A2 CSGALNACT2 CYB5A CYCS ELOVL4 FAM210B FAM3C FAXDC2 FUNDC2 FXYD3 GAST GPR152 GRM2 HBG2 HSD17B13 LAPTM5 LRCH4 MFSD6 NINJ1 NRM NSG1 NXPE3 ORMDL2 PNLIPRP1 REEP4 SLC10A1 SLC10A6 SLC13A3 SLC22A2 SLC35A4 SLC35B2 SLC38A7 SPP1 STOM TMEM115 TMEM14B TMEM14C TMEM201 TMEM31 TMEM51 TMEM60 TMEM79 TNF TNFRSF10C UBIAD1 VAMP1 VAMP4 VAMP5 VMP1 WFDC2 ZDHHC15
Entrez ID		6305	1727
HPRD ID		06788	08942
Ensembl ID		ENSG00000100241	ENSG00000100243
Uniprot IDs		O95248	P00387
PDB IDs			1M91 1UMK
Enriched GO Terms of Interacting Partners?
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