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S100A9 and MAGEA3
Data Source:
BioGRID
(two hybrid)
S100A9
MAGEA3
Description
S100 calcium binding protein A9
MAGE family member A3
Image
GO Annotations
Cellular Component
Extracellular Region
Extracellular Space
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Cytoskeleton
Plasma Membrane
Cell Junction
Secretory Granule Lumen
Collagen-containing Extracellular Matrix
Extracellular Exosome
Endoplasmic Reticulum
Molecular Function
Calcium Ion Binding
Protein Binding
Microtubule Binding
Zinc Ion Binding
Antioxidant Activity
Toll-like Receptor 4 Binding
Calcium-dependent Protein Binding
Arachidonic Acid Binding
RAGE Receptor Binding
Protein Binding
Caspase Binding
Biological Process
Cytokine Production
Toll-like Receptor Signaling Pathway
Leukocyte Migration Involved In Inflammatory Response
Chronic Inflammatory Response
Autophagy
Apoptotic Process
Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Inflammatory Response
Cell-cell Signaling
Positive Regulation Of Neuron Projection Development
Astrocyte Development
Peptidyl-cysteine S-nitrosylation
Antimicrobial Humoral Response
Positive Regulation Of Cell Growth
Neutrophil Chemotaxis
Sequestering Of Zinc Ion
Response To Lipopolysaccharide
Chemokine Production
Autocrine Signaling
Peptidyl-cysteine S-trans-nitrosylation
Modulation Of Process Of Other Organism
Defense Response To Bacterium
Neutrophil Degranulation
Innate Immune Response
Regulation Of Integrin Biosynthetic Process
Positive Regulation Of Inflammatory Response
Defense Response To Fungus
Positive Regulation Of NF-kappaB Transcription Factor Activity
Regulation Of Cytoskeleton Organization
Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide
Neutrophil Aggregation
Cellular Oxidant Detoxification
Positive Regulation Of Intrinsic Apoptotic Signaling Pathway
Negative Regulation Of Protein Processing
Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Negative Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway
Pathways
RHO GTPases Activate NADPH Oxidases
Regulation of TLR by endogenous ligand
Neutrophil degranulation
Metal sequestration by antimicrobial proteins
Drugs
Calcium
Zinc
Zinc acetate
Zinc chloride
Zinc sulfate, unspecified form
Diseases
GWAS
Asthma (
31619474
)
Basophil percentage of white cells (
32888494
)
Matrix metalloproteinase-8 levels (
29212897
)
Interacting Genes
12 interacting genes:
CDC42
EGFR
MAGEA1
MAGEA3
MAGEA6
MAPK14
NCF2
PTEN
S100A8
S100B
TUBA1A
TUBB
16 interacting genes:
ACOT7
BCL7B
C17orf49
CINP
DNM1L
ENOX2
EXOC5
HLA-DRB1
HTT
IQSEC1
KIF27
LSM2
PCYT1A
RUSC1
S100A9
STAMBPL1
Entrez ID
6280
4102
HPRD ID
00472
02166
Ensembl ID
ENSG00000163220
ENSG00000221867
Uniprot IDs
P06702
P43357
PDB IDs
1IRJ
1XK4
4GGF
4XJK
5I8N
5W1F
6DS2
1QEW
4V0P
5BRZ
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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