Wiki-MPM
About
Search
Browse
People
Funding
Updates
Search
S100A9 and S100A8
Data Source:
HPRD
(two hybrid, in vitro)
S100A9
S100A8
Description
S100 calcium binding protein A9
S100 calcium binding protein A8
Image
GO Annotations
Cellular Component
Extracellular Region
Extracellular Space
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Cytoskeleton
Plasma Membrane
Cell Junction
Secretory Granule Lumen
Collagen-containing Extracellular Matrix
Extracellular Exosome
Extracellular Region
Extracellular Space
Nucleus
Cytosol
Cytoskeleton
Plasma Membrane
Secretory Granule Lumen
Intermediate Filament Cytoskeleton
Collagen-containing Extracellular Matrix
Extracellular Exosome
Molecular Function
Calcium Ion Binding
Protein Binding
Microtubule Binding
Zinc Ion Binding
Antioxidant Activity
Toll-like Receptor 4 Binding
Calcium-dependent Protein Binding
Arachidonic Acid Binding
RAGE Receptor Binding
Calcium Ion Binding
Protein Binding
Microtubule Binding
Zinc Ion Binding
Toll-like Receptor 4 Binding
Calcium-dependent Protein Binding
Arachidonic Acid Binding
RAGE Receptor Binding
Biological Process
Cytokine Production
Toll-like Receptor Signaling Pathway
Leukocyte Migration Involved In Inflammatory Response
Chronic Inflammatory Response
Autophagy
Apoptotic Process
Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Inflammatory Response
Cell-cell Signaling
Positive Regulation Of Neuron Projection Development
Astrocyte Development
Peptidyl-cysteine S-nitrosylation
Antimicrobial Humoral Response
Positive Regulation Of Cell Growth
Neutrophil Chemotaxis
Sequestering Of Zinc Ion
Response To Lipopolysaccharide
Chemokine Production
Autocrine Signaling
Peptidyl-cysteine S-trans-nitrosylation
Modulation Of Process Of Other Organism
Defense Response To Bacterium
Neutrophil Degranulation
Innate Immune Response
Regulation Of Integrin Biosynthetic Process
Positive Regulation Of Inflammatory Response
Defense Response To Fungus
Positive Regulation Of NF-kappaB Transcription Factor Activity
Regulation Of Cytoskeleton Organization
Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide
Neutrophil Aggregation
Cellular Oxidant Detoxification
Positive Regulation Of Intrinsic Apoptotic Signaling Pathway
Cytokine Production
Toll-like Receptor Signaling Pathway
Leukocyte Migration Involved In Inflammatory Response
Acute Inflammatory Response
Chronic Inflammatory Response
Positive Regulation Of Peptide Secretion
Autophagy
Apoptotic Process
Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Inflammatory Response
Response To Zinc Ion
Astrocyte Development
Peptidyl-cysteine S-nitrosylation
Antimicrobial Humoral Response
Positive Regulation Of Cell Growth
Neutrophil Chemotaxis
Sequestering Of Zinc Ion
Response To Lipopolysaccharide
Chemokine Production
Autocrine Signaling
Wound Healing
Defense Response To Bacterium
Neutrophil Degranulation
Innate Immune Response
Response To Ethanol
Positive Regulation Of Inflammatory Response
Defense Response To Fungus
Positive Regulation Of NF-kappaB Transcription Factor Activity
Regulation Of Cytoskeleton Organization
Neutrophil Aggregation
Positive Regulation Of Intrinsic Apoptotic Signaling Pathway
Pathways
RHO GTPases Activate NADPH Oxidases
Regulation of TLR by endogenous ligand
Neutrophil degranulation
Metal sequestration by antimicrobial proteins
RHO GTPases Activate NADPH Oxidases
Regulation of TLR by endogenous ligand
Neutrophil degranulation
Metal sequestration by antimicrobial proteins
Drugs
Calcium
Zinc
Zinc acetate
Zinc chloride
Zinc sulfate, unspecified form
Calcium
Zinc
Copper
Zinc acetate
Zinc chloride
Zinc sulfate, unspecified form
Diseases
GWAS
Asthma (
31619474
)
Basophil percentage of white cells (
32888494
)
Matrix metalloproteinase-8 levels (
29212897
)
Asthma (
31619474
)
Matrix metalloproteinase-8 levels (
29212897
)
Interacting Genes
12 interacting genes:
CDC42
EGFR
MAGEA1
MAGEA3
MAGEA6
MAPK14
NCF2
PTEN
S100A8
S100B
TUBA1A
TUBB
21 interacting genes:
APP
CDKN1A
CEACAM3
CHGB
ERG28
GDF9
IGSF21
KLC2
LRIF1
NCF2
PDCD11
PPIA
PRMT1
PTEN
RAB17
S100A9
TP53
TUBA1A
TUBA4A
TUBB
UNC119
Entrez ID
6280
6279
HPRD ID
00472
00471
Ensembl ID
ENSG00000163220
ENSG00000143546
Uniprot IDs
P06702
P05109
PDB IDs
1IRJ
1XK4
4GGF
4XJK
5I8N
5W1F
6DS2
1MR8
1XK4
4GGF
4XJK
5HLO
5HLV
5W1F
6DS2
Enriched GO Terms of Interacting Partners
?
Tagcloud
?
Tagcloud (Difference)
?
Tagcloud (Intersection)
?