S100A6 and SUGT1

Data Source:
HPRD (in vitro, in vivo)

		S100A6	SUGT1
Description		S100 calcium binding protein A6	SGT1 homolog, MIS12 kinetochore complex assembly cochaperone
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GO Annotations	Cellular Component	Ruffle Extracellular Region Nucleus Nuclear Envelope Cytoplasm Cytosol Plasma Membrane Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane Perinuclear Region Of Cytoplasm Collagen-containing Extracellular Matrix Extracellular Exosome	Ubiquitin Ligase Complex Kinetochore Nucleus Cytosol Protein-containing Complex
	Molecular Function	Calcium Ion Binding Protein Binding Tropomyosin Binding Zinc Ion Binding Ion Transmembrane Transporter Activity Protein Homodimerization Activity S100 Protein Binding Calcium-dependent Protein Binding	Protein Binding
	Biological Process	Signal Transduction Axonogenesis Ion Transmembrane Transport Positive Regulation Of Fibroblast Proliferation	Mitotic Cell Cycle Regulation Of Protein Stability Positive Regulation By Host Of Symbiont Catalytic Activity Protein Stabilization
Pathways			The NLRP3 inflammasome Purinergic signaling in leishmaniasis infection
Drugs		Calcium citrate Calcium Phosphate Calcium phosphate dihydrate
Diseases
GWAS		HDL cholesterol levels x short total sleep time interaction (2df test) ( 31719535)
Interacting Genes		17 interacting genes: ANXA11 ANXA2 CACYBP CEP20 CEP43 FAM25A FAM25C FAM25G FKBP4 GAPDH MDM2 OFD1 PEX5 PPID S100B SUGT1 TP53	17 interacting genes: BUB3 CSNK2A1 DSN1 HSP90AA1 HSPA4 MIS12 NR4A1 NSL1 PAXIP1 PHLPP1 PLK1 PMF1 PTGER4 S100A6 S100B S100P SKP1
Entrez ID		6277	10910
HPRD ID		00237	09160
Ensembl ID		ENSG00000197956	ENSG00000165416
Uniprot IDs		P06703	A8K7W3 B4DYC6 Q9Y2Z0
PDB IDs		1K8U 1K96 1K9K 1K9P 2M1K 4YBH	1RL1
Enriched GO Terms of Interacting Partners?
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