S100A6 and CEP43

Data Source:
BioGRID (pull down)

		S100A6	CEP43
Description		S100 calcium binding protein A6	centrosomal protein 43
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GO Annotations	Cellular Component	Ruffle Extracellular Region Nucleus Nuclear Envelope Cytoplasm Cytosol Plasma Membrane Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane Perinuclear Region Of Cytoplasm Collagen-containing Extracellular Matrix Extracellular Exosome	Nucleus Centrosome Centriole Cytosol Cell Projection Perinuclear Region Of Cytoplasm
	Molecular Function	Calcium Ion Binding Protein Binding Tropomyosin Binding Zinc Ion Binding Ion Transmembrane Transporter Activity Protein Homodimerization Activity S100 Protein Binding Calcium-dependent Protein Binding	Protein Binding Protein Kinase Binding Protein Tyrosine Kinase Inhibitor Activity Protein Homodimerization Activity
	Biological Process	Signal Transduction Axonogenesis Ion Transmembrane Transport Positive Regulation Of Fibroblast Proliferation	G2/M Transition Of Mitotic Cell Cycle Negative Regulation Of Protein Kinase Activity Positive Regulation Of Cell Population Proliferation Regulation Of G2/M Transition Of Mitotic Cell Cycle Positive Regulation Of Cell Growth Positive Regulation Of Cell Migration Microtubule Anchoring Negative Regulation Of Protein Tyrosine Kinase Activity Ciliary Basal Body-plasma Membrane Docking
Pathways			Signaling by cytosolic FGFR1 fusion mutants Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane Signaling by FGFR1 in disease AURKA Activation by TPX2
Drugs		Calcium citrate Calcium Phosphate Calcium phosphate dihydrate
Diseases
GWAS		HDL cholesterol levels x short total sleep time interaction (2df test) ( 31719535)
Interacting Genes		17 interacting genes: ANXA11 ANXA2 CACYBP CEP20 CEP43 FAM25A FAM25C FAM25G FKBP4 GAPDH MDM2 OFD1 PEX5 PPID S100B SUGT1 TP53	5 interacting genes: CEP19 NAGK PPP2R1B S100A6 VASP
Entrez ID		6277	11116
HPRD ID		00237	10392
Ensembl ID		ENSG00000197956	ENSG00000213066
Uniprot IDs		P06703	A0A087WV25 B4DH64 O95684
PDB IDs		1K8U 1K96 1K9K 1K9P 2M1K 4YBH	2D68
Enriched GO Terms of Interacting Partners?
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