TNFRSF17 and PEX16

Data Source:
BioGRID (two hybrid)

		TNFRSF17	PEX16
Description		TNF receptor superfamily member 17	peroxisomal biogenesis factor 16
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Endomembrane System Integral Component Of Membrane	Peroxisome Peroxisomal Membrane Integral Component Of Peroxisomal Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane
	Molecular Function	Protein Binding Signaling Receptor Activity	Protein Binding Protein C-terminus Binding
	Biological Process	Adaptive Immune Response Lymphocyte Homeostasis Signal Transduction Multicellular Organism Development Tumor Necrosis Factor-mediated Signaling Pathway	Protein Targeting To Peroxisome Peroxisome Organization Peroxisome Membrane Biogenesis Protein Import Into Peroxisome Matrix Protein To Membrane Docking ER-dependent Peroxisome Organization Protein Import Into Peroxisome Membrane ER-dependent Peroxisome Localization
Pathways		TNFs bind their physiological receptors	Class I peroxisomal membrane protein import Class I peroxisomal membrane protein import
Drugs		Belantamab mafodotin
Diseases			Zellweger syndrome spectrum, including: Zellweger syndrome (ZS); Adrenoleukodystrophy, neonatal (NALD); Infantile Refsum disease (IRD)
GWAS		Blood protein levels ( 30072576) Phenylephrine infusion rate during anesthesia ( 31455332) QT interval ( 19305408) Testicular germ cell tumor ( 26503584)	Alzheimer's disease or fasting glucose levels (pleiotropy) ( 30805717) Axial length ( 24144296)
Interacting Genes		8 interacting genes: CMTM7 PEX16 TMBIM6 TNFSF13 TNFSF13B TRAF1 TRAF2 TRAF3	26 interacting genes: AQP6 BDKRB2 CLEC10A CREB3L1 DEXI EBAG9 ERGIC3 FCER1G FFAR2 GPR152 KCNJ6 LEPROTL1 MFSD14B MMGT1 PDZK1IP1 PEX19 PEX3 PGRMC2 REEP4 SLC10A1 SLC10A6 SLC18A1 SLC35C2 TMX2 TNFRSF17 ZDHHC15
Entrez ID		608	9409
HPRD ID		00144	04526
Ensembl ID		ENSG00000048462	ENSG00000121680
Uniprot IDs		Q02223	Q9Y5Y5
PDB IDs		1OQD 1XU2 2KN1 4ZFO 6J7W
Enriched GO Terms of Interacting Partners?
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