TNFRSF17 and TNFSF13B

Data Source:
HPRD (in vivo, in vitro)

		TNFRSF17	TNFSF13B
Description		TNF receptor superfamily member 17	TNF superfamily member 13b
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GO Annotations	Cellular Component	Plasma Membrane Endomembrane System Integral Component Of Membrane	Extracellular Region Extracellular Space Cytoplasm Plasma Membrane Focal Adhesion Integral Component Of Membrane Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding Signaling Receptor Activity	Cytokine Activity Tumor Necrosis Factor Receptor Binding Protein Binding Receptor Ligand Activity
	Biological Process	Adaptive Immune Response Lymphocyte Homeostasis Signal Transduction Multicellular Organism Development Tumor Necrosis Factor-mediated Signaling Pathway	B Cell Homeostasis Positive Regulation Of Germinal Center Formation Immune Response Signal Transduction Positive Regulation Of B Cell Proliferation T Cell Costimulation B Cell Costimulation Tumor Necrosis Factor-mediated Signaling Pathway Positive Regulation Of T Cell Proliferation
Pathways		TNFs bind their physiological receptors	TNFR2 non-canonical NF-kB pathway TNFs bind their physiological receptors TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway
Drugs		Belantamab mafodotin	1,4-Dioxane Belimumab
Diseases
GWAS		Blood protein levels ( 30072576) Phenylephrine infusion rate during anesthesia ( 31455332) QT interval ( 19305408) Testicular germ cell tumor ( 26503584)	Apolipoprotein A1 levels ( 32203549) Blood protein levels ( 30072576) HDL cholesterol levels ( 32203549) IgG levels ( 28628107) Metabolite levels ( 23823483) Monocyte percentage of white cells ( 32888494) Myeloid white cell count ( 27863252) Non-albumin protein levels ( 29403010) Platelet count ( 32888494 27863252) Platelet distribution width ( 32888494 27863252) Plateletcrit ( 32888494 27863252) Tonsillectomy ( 27182965 28928442) Venous thromboembolism adjusted for sickle cell variant rs77121243-T ( 28203683) White blood cell count ( 27863252)
Interacting Genes		8 interacting genes: CMTM7 PEX16 TMBIM6 TNFSF13 TNFSF13B TRAF1 TRAF2 TRAF3	5 interacting genes: APP TNFRSF13B TNFRSF13C TNFRSF17 TNFSF13
Entrez ID		608	10673
HPRD ID		00144	04914
Ensembl ID		ENSG00000048462	ENSG00000102524
Uniprot IDs		Q02223	A0A0U5J7Q1 Q9Y275
PDB IDs		1OQD 1XU2 2KN1 4ZFO 6J7W	1JH5 1KD7 1KXG 1OQD 1OQE 1OSG 3V56 4V46 4ZCH 5Y9J 6FXN
Enriched GO Terms of Interacting Partners?
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