PEX16 and SLC10A1

Data Source:
BioGRID (two hybrid)

		PEX16	SLC10A1
Description		peroxisomal biogenesis factor 16	solute carrier family 10 member 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Peroxisome Peroxisomal Membrane Integral Component Of Peroxisomal Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane	Plasma Membrane Integral Component Of Plasma Membrane Basolateral Plasma Membrane
	Molecular Function	Protein Binding Protein C-terminus Binding	Virus Receptor Activity Protein Binding Bile Acid:sodium Symporter Activity
	Biological Process	Protein Targeting To Peroxisome Peroxisome Organization Peroxisome Membrane Biogenesis Protein Import Into Peroxisome Matrix Protein To Membrane Docking ER-dependent Peroxisome Organization Protein Import Into Peroxisome Membrane ER-dependent Peroxisome Localization	Sodium Ion Transport Regulation Of Gene Expression Bile Acid And Bile Salt Transport Response To Nutrient Levels Cellular Response To Drug Bile Acid Signaling Pathway Response To Ethanol Viral Entry Into Host Cell Transmembrane Transport Regulation Of Bile Acid Secretion Response To 17alpha-ethynylestradiol
Pathways		Class I peroxisomal membrane protein import Class I peroxisomal membrane protein import	Recycling of bile acids and salts
Drugs
Diseases		Zellweger syndrome spectrum, including: Zellweger syndrome (ZS); Adrenoleukodystrophy, neonatal (NALD); Infantile Refsum disease (IRD)
GWAS		Alzheimer's disease or fasting glucose levels (pleiotropy) ( 30805717) Axial length ( 24144296)	Daytime sleep phenotypes ( 27126917) Metabolite levels ( 23823483) Triglyceride levels ( 30108155)
Interacting Genes		26 interacting genes: AQP6 BDKRB2 CLEC10A CREB3L1 DEXI EBAG9 ERGIC3 FCER1G FFAR2 GPR152 KCNJ6 LEPROTL1 MFSD14B MMGT1 PDZK1IP1 PEX19 PEX3 PGRMC2 REEP4 SLC10A1 SLC10A6 SLC18A1 SLC35C2 TMX2 TNFRSF17 ZDHHC15	91 interacting genes: ABHD16A ACSL5 AGPAT3 ARL6IP6 ASGR1 ATP6V0B BMP10 C2 C8A CFHR5 CLDN19 CMTM3 COX20 CXCL9 CYB5R3 DERL1 DGAT2L6 FA2H FAM241B FAXDC2 FCER1G FDFT1 FXYD3 FXYD6 FXYD6-FXYD2 GAST GDE1 GIMAP5 GOSR2 GPR151 GPR152 IFITM2 IFITM3 IFTAP LRP10 LSS MAL MALL MFSD6 MS4A1 MYADML2 NEU1 NINJ2 ORMDL1 ORMDL2 ORMDL3 OTOP3 PEDS1-UBE2V1 PEX16 PKMYT1 RUSF1 SACM1L SCAMP4 SELENOK SFT2D1 SFT2D2 SFXN1 SLC12A7 SLC16A13 SLC25A46 SLC29A2 SLC35E4 SLC38A1 SLC38A7 SLC41A1 SLC66A2 SLC7A3 SMPD2 STX7 TAP1 TFRC TMBIM1 TMEM119 TMEM120B TMEM121 TMEM147 TMEM222 TMEM234 TMEM239 TMEM242 TMEM60 TMUB2 TOMM6 TRARG1 TSPO2 TVP23B UNC50 VAMP3 YIF1A YIPF4 YIPF6
Entrez ID		9409	6554
HPRD ID		04526	01672
Ensembl ID		ENSG00000121680	ENSG00000100652
Uniprot IDs		Q9Y5Y5	B2RA41 Q14973
PDB IDs
Enriched GO Terms of Interacting Partners?
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