TNFRSF17 and TNFSF13

Data Source:
HPRD (in vitro)

		TNFRSF17	TNFSF13
Description		TNF receptor superfamily member 17	TNF superfamily member 13
Image
GO Annotations	Cellular Component	Plasma Membrane Endomembrane System Integral Component Of Membrane	Extracellular Region Extracellular Space Nucleoplasm Cytoplasm Cytosol Extracellular Exosome
	Molecular Function	Protein Binding Signaling Receptor Activity	Cytokine Activity Tumor Necrosis Factor Receptor Binding Receptor Ligand Activity
	Biological Process	Adaptive Immune Response Lymphocyte Homeostasis Signal Transduction Multicellular Organism Development Tumor Necrosis Factor-mediated Signaling Pathway	Immune Response Signal Transduction Positive Regulation Of Cell Population Proliferation Tumor Necrosis Factor-mediated Signaling Pathway Regulation Of MRNA Stability Positive Regulation Of Isotype Switching To IgA Isotypes
Pathways		TNFs bind their physiological receptors	HuR (ELAVL1) binds and stabilizes mRNA TNFs bind their physiological receptors
Drugs		Belantamab mafodotin
Diseases
GWAS		Blood protein levels ( 30072576) Phenylephrine infusion rate during anesthesia ( 31455332) QT interval ( 19305408) Testicular germ cell tumor ( 26503584)	Albumin-globulin ratio ( 29403010) Bitter alcoholic beverage consumption ( 31046077) Brain morphology (MOSTest) ( 32665545) Chin dimples ( 27182965) Composite immunoglobulin trait (IgA x IgG x IgM) ( 28628107) Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Diastolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858) IgA levels ( 22864923 28628107) IgA nephropathy ( 26028593 25305756 22197929) IgM levels ( 23118916) Myopia ( 27182965) Non-albumin protein levels ( 22558069 29403010) Serum total protein level ( 29403010) Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Systolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858)
Interacting Genes		8 interacting genes: CMTM7 PEX16 TMBIM6 TNFSF13 TNFSF13B TRAF1 TRAF2 TRAF3	13 interacting genes: CAMK1D FAS FURIN KRAS PIK3CA SDC2 SGTB TNFRSF11B TNFRSF13B TNFRSF14 TNFRSF17 TNFRSF1A TNFSF13B
Entrez ID		608	8741
HPRD ID		00144	05128
Ensembl ID		ENSG00000048462	ENSG00000161955
Uniprot IDs		Q02223	B3KR02 O75888 Q2QBA2
PDB IDs		1OQD 1XU2 2KN1 4ZFO 6J7W	4ZCH
Enriched GO Terms of Interacting Partners?
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