TNFSF13B and TNFRSF13C

Data Source:
HPRD (in vivo, in vitro)

		TNFSF13B	TNFRSF13C
Description		TNF superfamily member 13b	TNF receptor superfamily member 13C
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GO Annotations	Cellular Component	Extracellular Region Extracellular Space Cytoplasm Plasma Membrane Focal Adhesion Integral Component Of Membrane Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm	Plasma Membrane External Side Of Plasma Membrane Integral Component Of Membrane
	Molecular Function	Cytokine Activity Tumor Necrosis Factor Receptor Binding Protein Binding Receptor Ligand Activity	Signaling Receptor Activity
	Biological Process	B Cell Homeostasis Positive Regulation Of Germinal Center Formation Immune Response Signal Transduction Positive Regulation Of B Cell Proliferation T Cell Costimulation B Cell Costimulation Tumor Necrosis Factor-mediated Signaling Pathway Positive Regulation Of T Cell Proliferation	Adaptive Immune Response Positive Regulation Of B Cell Proliferation T Cell Costimulation B Cell Costimulation Tumor Necrosis Factor-mediated Signaling Pathway Positive Regulation Of T Cell Proliferation
Pathways		TNFR2 non-canonical NF-kB pathway TNFs bind their physiological receptors TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway	TNFR2 non-canonical NF-kB pathway TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway
Drugs		1,4-Dioxane Belimumab
Diseases			Common variable immunodeficiency (CVID), including the following four diseases: Inducible T Cell costimulator (ICOS) defect; TACI defect; CD19 defect; BAFFR defect
GWAS		Apolipoprotein A1 levels ( 32203549) Blood protein levels ( 30072576) HDL cholesterol levels ( 32203549) IgG levels ( 28628107) Metabolite levels ( 23823483) Monocyte percentage of white cells ( 32888494) Myeloid white cell count ( 27863252) Non-albumin protein levels ( 29403010) Platelet count ( 32888494 27863252) Platelet distribution width ( 32888494 27863252) Plateletcrit ( 32888494 27863252) Tonsillectomy ( 27182965 28928442) Venous thromboembolism adjusted for sickle cell variant rs77121243-T ( 28203683) White blood cell count ( 27863252)	Processed meat consumption ( 32066663) Schizophrenia ( 25056061 29483656)
Interacting Genes		5 interacting genes: APP TNFRSF13B TNFRSF13C TNFRSF17 TNFSF13	2 interacting genes: TNFSF13B TRAF3
Entrez ID		10673	115650
HPRD ID		04914	05883
Ensembl ID		ENSG00000102524	ENSG00000159958
Uniprot IDs		A0A0U5J7Q1 Q9Y275	Q5H8V1 Q96RJ3
PDB IDs		1JH5 1KD7 1KXG 1OQD 1OQE 1OSG 3V56 4V46 4ZCH 5Y9J 6FXN	1MPV 1OQE 1OSX 2HFG 3V56 4V46
Enriched GO Terms of Interacting Partners?
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