RCVRN and GRK6

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vivo)

		RCVRN	GRK6
Description		recoverin	G protein-coupled receptor kinase 6
Image
GO Annotations	Cellular Component	Photoreceptor Outer Segment Photoreceptor Inner Segment Membrane Dendrite Perikaryon	Plasma Membrane Membrane
	Molecular Function	Calcium Ion Binding Calcium Sensitive Guanylate Cyclase Activator Activity	G Protein-coupled Receptor Kinase Activity Protein Binding ATP Binding Beta-adrenergic Receptor Kinase Activity
	Biological Process	Signal Transduction Visual Perception Phototransduction Positive Regulation Of Guanylate Cyclase Activity Regulation Of Calcium Ion Transport	Protein Phosphorylation G Protein-coupled Receptor Signaling Pathway Regulation Of G Protein-coupled Receptor Signaling Pathway Wnt Signaling Pathway
Pathways		Inactivation, recovery and regulation of the phototransduction cascade Inactivation, recovery and regulation of the phototransduction cascade	G alpha (s) signalling events
Drugs		Myristic acid
Diseases
GWAS			Activated partial thromboplastin time ( 22703881) Blood protein levels ( 28240269) Cardiac troponin-I levels ( 31014085) Chronic kidney disease ( 20383146) Extremely high intelligence ( 29520040) Glycine levels ( 30837465) Intelligence (MTAG) ( 29326435) Metabolite levels ( 22916037) Neutrophil percentage of white cells ( 32888494) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		11 interacting genes: CAV1 GIT2 GRK1 GRK2 GRK5 GRK6 IL15RA PQBP1 SMAD3 TGFBR2 TOP1	19 interacting genes: ADRB2 BDKRB2 CHRM3 EDNRA EDNRB FBXO7 FSHR GIT1 ITGA5 KCNIP3 LTB4R PRSS23 RCVRN RHO SLC9A3R1 SNCA SNCB SNCG TBXA2R
Entrez ID		5957	2870
HPRD ID		01558	02925
Ensembl ID		ENSG00000109047	ENSG00000198055
Uniprot IDs		P35243	B3KPS5 P43250
PDB IDs		2D8N	2ACX 3NYN 3NYO
Enriched GO Terms of Interacting Partners?
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