RCVRN and GRK1

Data Source:
HPRD (in vitro)

		RCVRN	GRK1
Description		recoverin	G protein-coupled receptor kinase 1
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GO Annotations	Cellular Component	Photoreceptor Outer Segment Photoreceptor Inner Segment Membrane Dendrite Perikaryon	Photoreceptor Disc Membrane
	Molecular Function	Calcium Ion Binding Calcium Sensitive Guanylate Cyclase Activator Activity	Protein Kinase Activity G Protein-coupled Receptor Kinase Activity ATP Binding Rhodopsin Kinase Activity
	Biological Process	Signal Transduction Visual Perception Phototransduction Positive Regulation Of Guanylate Cyclase Activity Regulation Of Calcium Ion Transport	Visual Perception Regulation Of G Protein-coupled Receptor Signaling Pathway Rhodopsin Mediated Signaling Pathway Regulation Of Rhodopsin Mediated Signaling Pathway Protein Autophosphorylation
Pathways		Inactivation, recovery and regulation of the phototransduction cascade Inactivation, recovery and regulation of the phototransduction cascade	Inactivation, recovery and regulation of the phototransduction cascade Inactivation, recovery and regulation of the phototransduction cascade
Drugs		Myristic acid
Diseases			Congenital stationary night blindness (CSNB), including: CSNB type 1 (CSNB1); CSNB type 2 (CSNB2); CSNB autosomal dominant (CSNBAD); Oguchi disease/ CSNB Oguchi type (CSNBO)
GWAS
Interacting Genes		11 interacting genes: CAV1 GIT2 GRK1 GRK2 GRK5 GRK6 IL15RA PQBP1 SMAD3 TGFBR2 TOP1	9 interacting genes: ADRB2 CALM1 CAV1 PDE6D RCVRN RHO SNCA SNCB SNCG
Entrez ID		5957	6011
HPRD ID		01558	01585
Ensembl ID		ENSG00000109047	ENSG00000185974
Uniprot IDs		P35243	Q15835
PDB IDs		2D8N	5AFP
Enriched GO Terms of Interacting Partners?
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