S100B and ADTRP

Data Source:
BioGRID (two hybrid)

		S100B	ADTRP
Description		S100 calcium binding protein B	androgen dependent TFPI regulating protein
Image			No pdb structure
GO Annotations	Cellular Component	Ruffle Extracellular Region Extracellular Space Nucleus Nucleoplasm Cytoplasm Cytosol Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm	Caveola Cell Surface Membrane Integral Component Of Membrane
	Molecular Function	Calcium Ion Binding Protein Binding Zinc Ion Binding Identical Protein Binding Protein Homodimerization Activity S100 Protein Binding Tau Protein Binding Calcium-dependent Protein Binding RAGE Receptor Binding	Protein Binding Hydrolase Activity
	Biological Process	Axonogenesis Central Nervous System Development Learning Or Memory Positive Regulation Of Cell Population Proliferation Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Innate Immune Response	Positive Regulation Of Protein Phosphorylation Cell Migration Involved In Sprouting Angiogenesis Negative Regulation Of Leukocyte Migration Negative Regulation Of Extracellular Matrix Constituent Secretion Positive Regulation Of Gene Expression Negative Regulation Of Blood Coagulation Long-chain Fatty Acid Catabolic Process Protein Kinase B Signaling Negative Regulation Of Protein Secretion Cellular Response To Steroid Hormone Stimulus Cellular Response To Oxidised Low-density Lipoprotein Particle Stimulus Negative Regulation Of Leukocyte Cell-cell Adhesion Negative Regulation Of Lymphocyte Migration
Pathways		Nuclear signaling by ERBB4 TAK1 activates NFkB by phosphorylation and activation of IKKs complex Advanced glycosylation endproduct receptor signaling Advanced glycosylation endproduct receptor signaling TRAF6 mediated NF-kB activation
Drugs		Olopatadine Calcium N-Formylmethionine Arundic acid (Z)-2-[2-(4-methylpiperazin-1-yl)benzyl]diazenecarbothioamide 2-[(5-hex-1-yn-1-ylfuran-2-yl)carbonyl]-N-methylhydrazinecarbothioamide Calcium citrate Calcium Phosphate Calcium phosphate dihydrate
Diseases
GWAS		Cerebrospinal fluid t-tau:AB1-42 ratio ( 28641921) Lymphocyte counts ( 22286170)	Apolipoprotein B levels ( 32203549) Body mass index ( 26426971) Daytime sleep phenotypes ( 27126917) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Loneliness ( 29970889) Loneliness (MTAG) ( 29970889) Refractive error ( 32231278) Simvastatin-induced myopathy ( 31220337) Social science traits (pleiotropy) (HIPO component 1) ( 30289880) Spatial processing ( 31596458) Thrombosis ( 26908601)
Interacting Genes		46 interacting genes: ADTRP AGER AGTRAP AHNAK ANXA6 BCL2L2 CACYBP CALM1 CAPZA1 CEP20 CT45A5 DES DNAJC30 FBXO7 FBXW5 GFAP GUCY2D IMP4 IMPA1 IQGAP1 LNX1 MAL2 MAPT MDM2 MDM4 NDRG1 NKAPD1 PGM1 RABAC1 S100A1 S100A11 S100A2 S100A4 S100A6 S100A9 S100P S100Z SDCBP SPG21 STK38 SUGT1 TMEM159 TMEM239 TNIP1 TP53 VAV1	5 interacting genes: CMTM7 CREB3 S100B TMED8 VTN
Entrez ID		6285	84830
HPRD ID		01505	12836
Ensembl ID		ENSG00000160307	ENSG00000111863
Uniprot IDs		A0A0S2Z4C5 P04271	Q96IZ2
PDB IDs		1MQ1 1UWO 2H61 2M49 2PRU 3CZT 3D0Y 3D10 3HCM 4XYN 5CSF 5CSI 5CSJ 5CSN 5D7F
Enriched GO Terms of Interacting Partners?
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