RECQL and PLEKHA5

Data Source:
BioGRID (proximity labelling technology)

		RECQL	PLEKHA5
Description		RecQ like helicase	pleckstrin homology domain containing A5
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Chromosome Cytoplasm Membrane	Nucleoplasm Cytosol Postsynaptic Density Membrane Glutamatergic Synapse
	Molecular Function	DNA Binding DNA Helicase Activity Protein Binding ATP Binding Four-way Junction Helicase Activity Annealing Helicase Activity 3'-5' DNA Helicase Activity	Protein Binding Phosphatidylinositol-5-phosphate Binding Phosphatidylinositol-3-phosphate Binding Phosphatidylinositol-4-phosphate Binding Phosphatidylinositol-3,5-bisphosphate Binding
	Biological Process	Double-strand Break Repair Via Homologous Recombination DNA Strand Renaturation DNA Unwinding Involved In DNA Replication DNA Repair DNA Recombination DNA Duplex Unwinding	Biological_process Reproductive System Development
Pathways			Synthesis of PIPs at the plasma membrane
Drugs
Diseases
GWAS		Blood protein levels ( 30072576)	Adult body size ( 32376654) Chronic mountain sickness ( 31417607) Daytime sleep phenotypes ( 27126917) Gut microbiota (bacterial taxa) ( 27694959) Gut microbiota (bacterial taxa, rank normal transformation method) ( 32572223) Pharmacokinetics of antiepileptic drugs in severe mental disorder (concentration drug ratio) ( 25944848) Platelet reactivity in response to clopidogrel treatment ( 32472697) Thalamus volume ( 31530798)
Interacting Genes		4 interacting genes: KPNA2 KPNA4 RPA1 UBC	31 interacting genes: ARHGEF9 BLOC1S6 CCDC186 CCDC88B CCDC92 CEP250 CEP350 DES EVPL EXTL3 KANSL1 KIF3A KRT19 KRT20 KTN1 LAMB2 LSM4 MAX PDZD11 PLEC PLEKHA6 PPP1R13B PROM1 SH3BP5L SOGA1 SPTAN1 SPTBN1 SRPK2 UPF1 WASH2P YWHAG
Entrez ID		5965	54477
HPRD ID		02762	09684
Ensembl ID		ENSG00000004700	ENSG00000052126
Uniprot IDs		A0A024RAV2 P46063	A0A024RAY7 Q9HAU0
PDB IDs		2V1X 2WWY 4U7D 6JTZ	2DKP
Enriched GO Terms of Interacting Partners?
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