PRPH2 and CNGB1

Data Source:
HPRD (in vitro)

		PRPH2	CNGB1
Description		peripherin 2	cyclic nucleotide gated channel subunit beta 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Photoreceptor Outer Segment Photoreceptor Inner Segment Integral Component Of Plasma Membrane Integral Component Of Membrane	Golgi Membrane Photoreceptor Outer Segment Plasma Membrane Intracellular Cyclic Nucleotide Activated Cation Channel Complex Golgi-associated Vesicle Membrane Terminal Bouton Ciliary Membrane Transmembrane Transporter Complex
	Molecular Function	Protein Binding Protein Homodimerization Activity	Intracellular CAMP-activated Cation Channel Activity Intracellular CGMP-activated Cation Channel Activity Protein Binding Ligand-gated Ion Channel Activity CAMP Binding CGMP Binding Protein-containing Complex Binding
	Biological Process	Cell Adhesion Visual Perception Photoreceptor Cell Outer Segment Organization Detection Of Light Stimulus Involved In Visual Perception Protein Homooligomerization Protein Heterooligomerization Retina Development In Camera-type Eye	Retina Homeostasis Cation Transport Visual Perception Sensory Perception Of Smell Rhodopsin Mediated Signaling Pathway Regulation Of Rhodopsin Mediated Signaling Pathway Protein Localization To Organelle Photoreceptor Cell Outer Segment Organization Photoreceptor Cell Maintenance Detection Of Light Stimulus Involved In Visual Perception Regulation Of Cytosolic Calcium Ion Concentration Cation Transmembrane Transport
Pathways			Activation of the phototransduction cascade Inactivation, recovery and regulation of the phototransduction cascade VxPx cargo-targeting to cilium VxPx cargo-targeting to cilium
Drugs
Diseases		Vitelliform macular dystrophy, including: Best disease / Juvenile vitelliform macular dystrophy (VMD2) ; Adult-onset vitelliform macular dystrophy (AVMD) Retinitis pigmentosa (RP) Macular degeneration, including: Age-related macular degeneration (ARMD); Patterned dystrophy of retinal pigment epithelium (PDREP); Retinal macular dystrophy 2 (MCDR2); X-linked atrophic macular degeneration (MDXLA)	Retinitis pigmentosa (RP)
GWAS		Pulse pressure ( 27841878)	Initial alcohol sensitivity ( 30276832) Low density lipoprotein cholesterol levels ( 32154731) Prudent dietary pattern ( 28644415) Sensory peripheral neuropathy in microtubule targeting agent-treated breast cancer ( 32562552) Triglyceride levels ( 32154731)
Interacting Genes		4 interacting genes: CNGB1 GRAP2 PRPH ROM1	3 interacting genes: ABCA4 PNN PRPH2
Entrez ID		5961	1258
HPRD ID		01553	07204
Ensembl ID		ENSG00000112619	ENSG00000070729
Uniprot IDs		P23942	Q14028
PDB IDs
Enriched GO Terms of Interacting Partners?
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