CNGB1 and PNN

Data Source:
HPRD (two hybrid)

		CNGB1	PNN
Description		cyclic nucleotide gated channel subunit beta 1	pinin, desmosome associated protein
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Photoreceptor Outer Segment Plasma Membrane Intracellular Cyclic Nucleotide Activated Cation Channel Complex Golgi-associated Vesicle Membrane Terminal Bouton Ciliary Membrane Transmembrane Transporter Complex	Intermediate Filament Plasma Membrane Cell-cell Junction Membrane Nuclear Speck Desmosome Exon-exon Junction Complex Catalytic Step 2 Spliceosome
	Molecular Function	Intracellular CAMP-activated Cation Channel Activity Intracellular CGMP-activated Cation Channel Activity Protein Binding Ligand-gated Ion Channel Activity CAMP Binding CGMP Binding Protein-containing Complex Binding	DNA Binding RNA Binding Structural Molecule Activity Protein Binding
	Biological Process	Retina Homeostasis Cation Transport Visual Perception Sensory Perception Of Smell Rhodopsin Mediated Signaling Pathway Regulation Of Rhodopsin Mediated Signaling Pathway Protein Localization To Organelle Photoreceptor Cell Outer Segment Organization Photoreceptor Cell Maintenance Detection Of Light Stimulus Involved In Visual Perception Regulation Of Cytosolic Calcium Ion Concentration Cation Transmembrane Transport	MRNA Splicing, Via Spliceosome Cell Adhesion
Pathways		Activation of the phototransduction cascade Inactivation, recovery and regulation of the phototransduction cascade VxPx cargo-targeting to cilium VxPx cargo-targeting to cilium
Drugs
Diseases		Retinitis pigmentosa (RP)
GWAS		Initial alcohol sensitivity ( 30276832) Low density lipoprotein cholesterol levels ( 32154731) Prudent dietary pattern ( 28644415) Sensory peripheral neuropathy in microtubule targeting agent-treated breast cancer ( 32562552) Triglyceride levels ( 32154731)
Interacting Genes		3 interacting genes: ABCA4 PNN PRPH2	18 interacting genes: CNGB1 CSNK2A1 CTBP1 CTBP2 DYNC1I2 KRT18 KRT19 KRT27 KRT8 PNISR PPIG PRPF4B RNPS1 SRPK2 SRRM2 SRSF4 YWHAG ZCCHC17
Entrez ID		1258	5411
HPRD ID		07204	04401
Ensembl ID		ENSG00000070729	ENSG00000100941
Uniprot IDs		Q14028	Q9H307
PDB IDs
Enriched GO Terms of Interacting Partners?
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