SENP2 and HCCS

Data Source:
BioGRID (two hybrid)

		SENP2	HCCS
Description		SUMO specific peptidase 2	holocytochrome c synthase
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nuclear Pore Nucleoplasm Cytosol PML Body Nuclear Membrane	Mitochondrion Mitochondrial Inner Membrane Membrane
	Molecular Function	Protein Binding SUMO-specific Protease Activity Protein Domain Specific Binding SUMO-specific Endopeptidase Activity SUMO-specific Isopeptidase Activity	Holocytochrome-c Synthase Activity Protein Binding Heme Binding Metal Ion Binding
	Biological Process	Positive Regulation Of Protein Phosphorylation Heart Development Dorsal/ventral Axis Specification Protein Transport Wnt Signaling Pathway Protein Sumoylation Protein Desumoylation Regulation Of Wnt Signaling Pathway Negative Regulation Of Protein Ubiquitination Positive Regulation Of Protein Ubiquitination Protein Destabilization Negative Regulation Of Protein Binding Regulation Of DNA Endoreduplication Negative Regulation Of Chromatin Binding Fat Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II MRNA Transport Trophoblast Giant Cell Differentiation Labyrinthine Layer Development Regulation Of G1/S Transition Of Mitotic Cell Cycle	Animal Organ Morphogenesis Cytochrome C-heme Linkage Protein Phosphopantetheinylation
Pathways		SUMO is proteolytically processed
Drugs
Diseases			Anophthalmia and microphthalmia (A/M)
GWAS		Diastolic blood pressure ( 28135244 27841878) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Estimated glomerular filtration rate ( 31152163 31015462) Height ( 28552196) Hip circumference ( 28552196) JT interval ( 29874175) PR interval ( 30046033 32439900) QRS duration ( 30012220) Seborrheic dermatitis ( 29203360) Systolic blood pressure ( 27841878 26969751)	Cognitive performance ( 19734545)
Interacting Genes		38 interacting genes: ACSF2 AGTRAP APOC2 APOC4 APP ARL6IP1 ARMC12 AXIN1 CDCA5 CDK5RAP2 DAXX ERCC6 FUNDC1 FZR1 HCCS IKBKG KASH5 KPNA1 KPNB1 LMNA MYC NACC1 NEDD4L NUP153 PML RANGAP1 RETREG3 RPRM SDR16C5 STK38 SUMO1 SUMO2 SUMO3 SYNE4 TMEM239 TNFRSF10D TPD52 TRIM63	3 interacting genes: CIDEB SENP2 SNX1
Entrez ID		59343	3052
HPRD ID		07002	02085
Ensembl ID		ENSG00000163904	ENSG00000004961
Uniprot IDs		Q9HC62	A0A024RBY9 P53701
PDB IDs		1TGZ 1TH0 2IO0 2IO1 2IO2 2IO3 3ZO5 5AEK
Enriched GO Terms of Interacting Partners?
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