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RBL1 and AOX1
Data Source:
BioGRID
(two hybrid)
RBL1
AOX1
Description
RB transcriptional corepressor like 1
aldehyde oxidase 1
Image
GO Annotations
Cellular Component
Chromatin
Nucleoplasm
Transcription Regulator Complex
Cytosol
Extracellular Exosome
Molecular Function
RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding
RNA Polymerase II Activating Transcription Factor Binding
Protein Binding
Transcription Factor Binding
Promoter-specific Chromatin Binding
Aldehyde Oxidase Activity
Iron Ion Binding
Electron Transfer Activity
Oxidoreductase Activity
Identical Protein Binding
Protein Homodimerization Activity
Molybdopterin Cofactor Binding
Flavin Adenine Dinucleotide Binding
NAD Binding
2 Iron, 2 Sulfur Cluster Binding
FAD Binding
Geranial:oxygen Oxidoreductase Activity
Heptaldehyde:oxygen Oxidoreductase Activity
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
Chromatin Organization
Cell Cycle
Negative Regulation Of Gene Expression
Viral Process
Cell Differentiation
Regulation Of Lipid Kinase Activity
Positive Regulation Of Transcription By RNA Polymerase II
Regulation Of Cell Division
Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle
Negative Regulation Of Cellular Senescence
Drug Metabolic Process
Electron Transport Chain
Vitamin B6 Metabolic Process
Pathways
Transcription of E2F targets under negative control by DREAM complex
Transcription of E2F targets under negative control by DREAM complex
Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1
G0 and Early G1
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest
G1/S-Specific Transcription
Cyclin D associated events in G1
Vitamins B6 activation to pyridoxal phosphate
Drugs
Cyclobenzaprine
Eniluracil
Diseases
Xanthinuria
GWAS
Height (
25429064
)
Mean corpuscular hemoglobin (
32888494
)
Mean corpuscular volume (
32888494
)
Mean reticulocyte volume (
32888494
)
Mean spheric corpuscular volume (
32888494
)
Red cell distribution width (
32888494
28957414
)
Hip circumference adjusted for BMI (
28552196
)
Intelligence (
22449649
)
Late-onset Alzheimer's disease (
27770636
)
Interacting Genes
54 interacting genes:
AOX1
BEGAIN
BRCA1
BRF1
CCNA1
CCNA2
CCND1
CCNE1
CDK2
CDK4
CDK6
CEBPA
CREG1
DGKZ
DHX30
DYRK1A
E2F1
E2F4
E2F5
EPHA2
FN1
GOLGA2
HDAC1
ID2
IRF3
KDM5A
KMT5C
LAMB2
MAPK6
MCM7
MYBL2
MYC
NR2E3
NR4A1
NUCB1
PHB
PLSCR1
PPP2R3A
RBBP8
RBBP9
RINT1
SMAD2
SMAD3
SMAD4
SMARCA4
SNRPD3
SNW1
SP1
SUV39H1
TAF1
TOP1
TP53BP1
TSC22D2
USP4
6 interacting genes:
ABCA1
CRKL
ERRFI1
GK
RBL1
RCHY1
Entrez ID
5933
316
HPRD ID
00312
07537
Ensembl ID
ENSG00000080839
ENSG00000138356
Uniprot IDs
P28749
Q06278
PDB IDs
1H28
4YOO
4YOS
4YOZ
5TUV
4UHW
4UHX
5EPG
6Q6Q
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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