AOX1 and GK

Data Source:
BioGRID (two hybrid)

		AOX1	GK
Description		aldehyde oxidase 1	glycerol kinase
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol Extracellular Exosome	Mitochondrion Mitochondrial Outer Membrane Cytosol Extracellular Exosome
	Molecular Function	Aldehyde Oxidase Activity Iron Ion Binding Electron Transfer Activity Oxidoreductase Activity Identical Protein Binding Protein Homodimerization Activity Molybdopterin Cofactor Binding Flavin Adenine Dinucleotide Binding NAD Binding 2 Iron, 2 Sulfur Cluster Binding FAD Binding Geranial:oxygen Oxidoreductase Activity Heptaldehyde:oxygen Oxidoreductase Activity	Glycerol Kinase Activity Protein Binding ATP Binding Phosphotransferase Activity, Alcohol Group As Acceptor
	Biological Process	Drug Metabolic Process Electron Transport Chain Vitamin B6 Metabolic Process	Glycerol Metabolic Process Triglyceride Metabolic Process Phosphorylation Triglyceride Biosynthetic Process Glycerol Catabolic Process Glycerol-3-phosphate Biosynthetic Process
Pathways		Vitamins B6 activation to pyridoxal phosphate	Triglyceride biosynthesis
Drugs		Cyclobenzaprine Eniluracil
Diseases		Xanthinuria	Glycerol kinase deficiency (GKD), including: Hyperglycerolemia; Chromosome Xp21 deletion syndrome; Adrenal hypoplasia, congenital (AHC); Duchenne muscular dystrophy (DMD)
GWAS		Hip circumference adjusted for BMI ( 28552196) Intelligence ( 22449649) Late-onset Alzheimer's disease ( 27770636)	Cardiovascular risk factors (age interaction) ( 20838585)
Interacting Genes		6 interacting genes: ABCA1 CRKL ERRFI1 GK RBL1 RCHY1	11 interacting genes: AOX1 APCS CLPTM1L CYP3A4 EIF4G1 FBXO28 GPD1 IPO13 NR4A1 OPLAH RXRA
Entrez ID		316	2710
HPRD ID		07537	08363
Ensembl ID		ENSG00000138356	ENSG00000198814
Uniprot IDs		Q06278	B4DH54 P32189
PDB IDs		4UHW 4UHX 5EPG 6Q6Q
Enriched GO Terms of Interacting Partners?
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