RBBP6 and KHDRBS3

Data Source:
BioGRID (two hybrid)

		RBBP6	KHDRBS3
Description		RB binding protein 6, ubiquitin ligase	KH RNA binding domain containing, signal transduction associated 3
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GO Annotations	Cellular Component	Chromosome Nucleolus Centrosome Cytosol Nuclear Speck Protein-containing Complex	Nucleus Nucleoplasm Protein-containing Complex
	Molecular Function	RNA Binding Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Protein Kinase Binding Ubiquitin Protein Ligase Activity	RNA Binding MRNA Binding Protein Binding SH3 Domain Binding Protein Domain Specific Binding Identical Protein Binding
	Biological Process	Protein Polyubiquitination In Utero Embryonic Development DNA Replication Regulation Of DNA Replication MRNA Processing Ubiquitin-dependent Protein Catabolic Process Cellular Response To DNA Damage Stimulus Multicellular Organism Growth Embryonic Organ Development Somite Development	Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Processing Viral Process Regulation Of MRNA Splicing, Via Spliceosome
Pathways		Antigen processing: Ubiquitination & Proteasome degradation	PTK6 Regulates Proteins Involved in RNA Processing
Drugs
Diseases
GWAS		Adult body size ( 32376654) Body mass index ( 28892062) Body size at age 10 ( 32376654) Brain structure ( 20171287) Chronotype ( 30696823) Obesity-related traits ( 23251661) Pulse pressure ( 27841878) Systolic blood pressure ( 27841878)	Chronotype ( 30696823) Disease progression in age-related macular degeneration ( 29346644) Polycystic ovary syndrome ( 25574032) Squamous cell lung carcinoma ( 28604730) Venous thromboembolism adjusted for sickle cell variant rs77121243-T ( 28203683)
Interacting Genes		40 interacting genes: ACOT13 ANAPC16 APOH ASGR1 CAPZA2 CASK CD81 CLK1 ETS1 EVA1C FAAP24 FBXO7 GLUL GRB2 HP KHDRBS3 LINC00305 LRCH4 MAD2L2 MDM2 MIR19A MIR19B1 NDUFB9 NEK6 PIAS1 PLG RB1 RBP4 RCC1L RPS14 SMN1 SPP1 TP53 TPT1 UBE2I UPF3B VAV2 YBX1 ZBTB38 ZFYVE9	54 interacting genes: AQP1 BAHD1 CACNA1A CCDC187 CCDC33 CNNM3 DMRT3 DOCK2 FBXO7 FUS HBZ HNRNPC HNRNPK INPP5D KHDRBS1 KHDRBS2 LMNTD2 LNX1 MARK4 MYPOP NCOA5 NELFB NUDT18 PCDHB14 PPP1R13B PRMT1 PRPF31 PRR3 PSMA1 PSMF1 PTBP2 RASAL3 RASD1 RBBP6 RBM3 RBM7 RBMX RBMY1A1 RFC3 RPH3AL SGSM2 SIAH1 SNRPC SNX18 SRSF9 TSGA10IP TYK2 U2AF2 YTHDC1 ZNF326 ZNF408 ZNF575 ZNF580 ZNF688
Entrez ID		5930	10656
HPRD ID		02964	10007
Ensembl ID		ENSG00000122257	ENSG00000131773
Uniprot IDs		Q7Z6E9	O75525
PDB IDs		2C7H 2YSA 2YUR 3ZTG 6E5X	5EL3 5ELR 5ELS 5ELT 5EMO
Enriched GO Terms of Interacting Partners?
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