KHDRBS3 and PTBP2

Data Source:
BioGRID (two hybrid, two hybrid)

		KHDRBS3	PTBP2
Description		KH RNA binding domain containing, signal transduction associated 3	polypyrimidine tract binding protein 2
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Protein-containing Complex	Nucleus Spliceosomal Complex Growth Cone Neuronal Cell Body
	Molecular Function	RNA Binding MRNA Binding Protein Binding SH3 Domain Binding Protein Domain Specific Binding Identical Protein Binding	RNA Binding MRNA Binding
	Biological Process	Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Processing Viral Process Regulation Of MRNA Splicing, Via Spliceosome	MRNA Splice Site Selection Spinal Cord Development Cerebellum Development Negative Regulation Of RNA Splicing Regulation Of RNA Splicing Regulation Of Neural Precursor Cell Proliferation
Pathways		PTK6 Regulates Proteins Involved in RNA Processing
Drugs
Diseases
GWAS		Chronotype ( 30696823) Disease progression in age-related macular degeneration ( 29346644) Polycystic ovary syndrome ( 25574032) Squamous cell lung carcinoma ( 28604730) Venous thromboembolism adjusted for sickle cell variant rs77121243-T ( 28203683)	Adult body size ( 32376654) Anorexia nervosa ( 31308545) Autism spectrum disorder ( 30804558) BMI (adjusted for smoking behaviour) ( 28443625) Body mass index ( 28892062 25673413 20935630 28448500) Body mass index (joint analysis main effects and physical activity interaction) ( 28448500) Body mass index (joint analysis main effects and smoking interaction) ( 28443625) Body mass index in physically inactive individuals ( 28448500) Body size at age 10 ( 32376654) Chronotype ( 30696823) Femoral neck bone mineral density and trunk fat mass adjusted by trunk lean mass ( 32239398) Headache ( 29397368) Hip circumference ( 25673412) Number of sexual partners ( 30643258) Reaction time ( 29844566) Regular attendance at a pub or social club ( 29970889) Schizophrenia ( 19571811 22688191) Smoking status (ever vs never smokers) ( 30643258) Trunk fat mass adjusted for trunk lean mass ( 32239398 30944420) Waist circumference ( 25673412)
Interacting Genes		54 interacting genes: AQP1 BAHD1 CACNA1A CCDC187 CCDC33 CNNM3 DMRT3 DOCK2 FBXO7 FUS HBZ HNRNPC HNRNPK INPP5D KHDRBS1 KHDRBS2 LMNTD2 LNX1 MARK4 MYPOP NCOA5 NELFB NUDT18 PCDHB14 PPP1R13B PRMT1 PRPF31 PRR3 PSMA1 PSMF1 PTBP2 RASAL3 RASD1 RBBP6 RBM3 RBM7 RBMX RBMY1A1 RFC3 RPH3AL SGSM2 SIAH1 SNRPC SNX18 SRSF9 TSGA10IP TYK2 U2AF2 YTHDC1 ZNF326 ZNF408 ZNF575 ZNF580 ZNF688	19 interacting genes: CALCOCO2 EIF5A2 ELAVL1 GOLGA2 HNRNPAB HNRNPC HNRNPD KHDRBS1 KHDRBS3 KHSRP MATR3 PCBP3 PUF60 QKI RBM10 RBM4 RBPMS2 SNRPA TOM1
Entrez ID		10656	58155
HPRD ID		10007	12233
Ensembl ID		ENSG00000131773	ENSG00000117569
Uniprot IDs		O75525	A0A6Q8PFE6 B4DSS8 B4DSU5 Q9UKA9
PDB IDs		5EL3 5ELR 5ELS 5ELT 5EMO	2CQ1 2MJU 4CQ1
Enriched GO Terms of Interacting Partners?
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