RAD52 and KPNA5

Data Source:
BioGRID (two hybrid)

		RAD52	KPNA5
Description		RAD52 homolog, DNA repair protein	karyopherin subunit alpha 5
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Protein-containing Complex Protein-DNA Complex	Nucleus Nucleoplasm Cytosol
	Molecular Function	DNA Binding Single-stranded DNA Binding Protein Binding Identical Protein Binding	Protein Binding Nuclear Localization Sequence Binding Nuclear Import Signal Receptor Activity
	Biological Process	Double-strand Break Repair Via Homologous Recombination DNA Recombinase Assembly Double-strand Break Repair DNA Recombination Mitotic Recombination Cellular Response To DNA Damage Stimulus DNA Double-strand Break Processing Involved In Repair Via Single-strand Annealing Cellular Response To Oxidative Stress Double-strand Break Repair Via Single-strand Annealing Regulation Of Nucleotide-excision Repair	NLS-bearing Protein Import Into Nucleus Modulation By Virus Of Host Cellular Process
Pathways		SUMOylation of DNA damage response and repair proteins HDR through Single Strand Annealing (SSA)	ISG15 antiviral mechanism NS1 Mediated Effects on Host Pathways
Drugs
Diseases
GWAS		Blood protein levels ( 29875488) Body mass index ( 26426971) Eosinophil percentage of granulocytes ( 27863252) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Immature fraction of reticulocytes ( 32888494) Lung cancer ( 22899653) Neutrophil percentage of granulocytes ( 27863252) Small cell lung carcinoma ( 28604730) Systolic blood pressure ( 30224653 30578418) Youthful appearance (self-reported) ( 32339537)	Early cardiac repolarization ( 31600170) Telomere length ( 21460395)
Interacting Genes		25 interacting genes: ABL1 AURKB DCP1A ERCC1 ERCC2 ERCC3 ERCC4 KPNA3 KPNA5 MCM2 MCM3 MEOX1 MEOX2 NFYC PAX5 PLK3 RAD51 RDM1 RPA1 RPA2 SEM1 SUMO1 TTK UBE2I WRN	28 interacting genes: ANP32A ANP32B ARNT BRMS1 CDKN1B DCPS EPAS1 FAM214B FBXO7 HIF1A HNRNPC IL32 KAT5 LMNB1 MLH1 NMNAT1 NRF1 NUP50 POLR3C POU6F2 RAD52 RBBP4 SPOP SPOPL TSEN54 TWIST1 WT1 ZNF326
Entrez ID		5893	3841
HPRD ID		11855	05179
Ensembl ID		ENSG00000002016	ENSG00000196911
Uniprot IDs		B7Z2G8 B7Z5Q6 F5GX32 P43351 Q5DR82	O15131
PDB IDs		1H2I 1KN0 5JRB 5XRZ 5XS0	4U2X
Enriched GO Terms of Interacting Partners?
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