KPNA5 and SPOPL

		KPNA5	SPOPL
Description		karyopherin subunit alpha 5	speckle type BTB/POZ protein like
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol	Nucleus Cytoplasm Cul3-RING Ubiquitin Ligase Complex
	Molecular Function	Protein Binding Nuclear Localization Sequence Binding Nuclear Import Signal Receptor Activity	Protein Binding Ubiquitin Protein Ligase Binding
	Biological Process	NLS-bearing Protein Import Into Nucleus Modulation By Virus Of Host Cellular Process	Protein Ubiquitination Regulation Of Proteolysis Negative Regulation Of Protein Ubiquitination Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Pathways		ISG15 antiviral mechanism NS1 Mediated Effects on Host Pathways	Hedgehog 'on' state
Drugs
Diseases
GWAS		Early cardiac repolarization ( 31600170) Telomere length ( 21460395)	Response to antipsychotic treatment ( 23241943)
Interacting Genes		28 interacting genes: ANP32A ANP32B ARNT BRMS1 CDKN1B DCPS EPAS1 FAM214B FBXO7 HIF1A HNRNPC IL32 KAT5 LMNB1 MLH1 NMNAT1 NRF1 NUP50 POLR3C POU6F2 RAD52 RBBP4 SPOP SPOPL TSEN54 TWIST1 WT1 ZNF326	6 interacting genes: ATF2 CREB5 EPS15 KPNA5 MYD88 RXRB
Entrez ID		3841	339745
HPRD ID		05179	11261
Ensembl ID		ENSG00000196911	ENSG00000144228
Uniprot IDs		O15131	Q6IQ16
PDB IDs		4U2X
Enriched GO Terms of Interacting Partners?
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