RAD21 and MSRB2

Data Source:
BioGRID (two hybrid)

		RAD21	MSRB2
Description		RAD21 cohesin complex component	methionine sulfoxide reductase B2
Image			No pdb structure
GO Annotations	Cellular Component	Chromosome, Centromeric Region Synaptonemal Complex Spindle Pole Nucleoplasm Chromosome Cytosol Cohesin Complex Membrane Nuclear Matrix Nuclear Mitotic Cohesin Complex Nuclear Meiotic Cohesin Complex	Cytoplasm Mitochondrion Cytosol
	Molecular Function	Chromatin Binding Protein Binding	Actin Binding Protein Binding Zinc Ion Binding Peptide-methionine (R)-S-oxide Reductase Activity L-methionine-(R)-S-oxide Reductase Activity
	Biological Process	Double-strand Break Repair DNA Recombination Regulation Of Transcription By RNA Polymerase II Apoptotic Process Mitotic Sister Chromatid Cohesion Synaptonemal Complex Assembly Reciprocal Meiotic Recombination Multicellular Organism Development Negative Regulation Of G2/M Transition Of Mitotic Cell Cycle Negative Regulation Of Mitotic Metaphase/anaphase Transition Positive Regulation Of Sister Chromatid Cohesion Cell Division Protein Localization To Chromatin Replication-born Double-strand Break Repair Via Sister Chromatid Exchange	Response To Oxidative Stress Actin Filament Polymerization Protein Repair
Pathways		Meiotic synapsis Separation of Sister Chromatids Establishment of Sister Chromatid Cohesion Cohesin Loading onto Chromatin Resolution of Sister Chromatid Cohesion SUMOylation of DNA damage response and repair proteins Estrogen-dependent gene expression	Protein repair
Drugs
Diseases
GWAS		Menopause (age at onset) ( 29773799)	Diisocyanate-induced asthma ( 25918132) Obesity-related traits ( 23251661)
Interacting Genes		30 interacting genes: CAPN1 CASP7 CFL1 CSTB DISC1 DYNLT1 FHL3 FLNB HNRNPH2 IL7R MSRB2 MT-CO2 NUMA1 PPP1R15A PPP1R15B PTEN RPL10 RPL13 RPL35A SMARCA5 SMC1A SSU72 STAG1 STAG2 SUMO2 TMSB4X TNFRSF14 WAPL WNT2B ZNF80	3 interacting genes: RAD21 TRAF2 ZDHHC17
Entrez ID		5885	22921
HPRD ID		05924	17606
Ensembl ID		ENSG00000164754	ENSG00000148450
Uniprot IDs		A0A024R9J0 O60216	Q9Y3D2
PDB IDs		4PJU 4PJW 4PK7 6QNX 6RRC 6RRK 6WG3 6WGE
Enriched GO Terms of Interacting Partners?
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