CFL2 and RAB2A

Data Source:
BioGRID (two hybrid)

		CFL2	RAB2A
Description		cofilin 2	RAB2A, member RAS oncogene family
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Space Cytoplasm Actin Cytoskeleton Nuclear Matrix Z Disc I Band Extracellular Exosome	Golgi Membrane Nucleus Lysosomal Membrane Endoplasmic Reticulum Membrane Golgi Apparatus Cytosol Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Melanosome Extracellular Exosome
	Molecular Function	Protein Binding Actin Filament Binding	GTPase Activity Protein Binding GTP Binding GDP Binding
	Biological Process	Skeletal Muscle Tissue Development Actin Filament Depolymerization Actin Filament Fragmentation Positive Regulation Of Actin Filament Depolymerization Sarcomere Organization Muscle Cell Cellular Homeostasis Cell Motility Actin Filament Severing	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Golgi Organization Protein Transport Post-translational Protein Modification
Pathways			Golgi Cisternae Pericentriolar Stack Reorganization RAB geranylgeranylation
Drugs
Diseases		Nemaline myopathy
GWAS		Atrial fibrillation ( 30061737 29892015) Hip circumference adjusted for BMI ( 28552196)	Autoimmune thyroid disease ( 32581359) Estimated glomerular filtration rate ( 31152163) Low density lipoprotein cholesterol levels ( 32154731) Neutrophil count ( 32888494) Systemic sclerosis ( 31672989) Total cholesterol levels ( 29083408)
Interacting Genes		13 interacting genes: ACTB ACTG1 CAP2 CFL1 DSTN LIMK1 POT1 RAB2A RNF4 SSH1 STK11 TRIM7 UBE2I	27 interacting genes: BLZF1 CBFB CCDC125 CFL2 FAM114A1 FAM114A2 FAM71A FAM71C FAM71F2 FRMD1 GAPDH GDI2 GOLGA2 GORASP2 HES6 ICA1 MAPK6 MAPKAPK3 PMAIP1 PRKCI RBSN RGS2 SGSM2 STAMBPL1 TBC1D25 TMEM70 TRIM7
Entrez ID		1073	5862
HPRD ID		03262	01539
Ensembl ID		ENSG00000165410	ENSG00000104388
Uniprot IDs		Q549N0 Q9Y281	A0A024R7V6 P61019
PDB IDs			1Z0A
Enriched GO Terms of Interacting Partners?
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