RAB1A and CHML

Data Source:
HPRD (in vitro)

		RAB1A	CHML
Description		RAB1A, member RAS oncogene family	CHM like Rab escort protein
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Early Endosome Endoplasmic Reticulum Golgi Apparatus Cytosol Endomembrane System Transport Vesicle Membrane Melanosome Extracellular Exosome	Nucleus Nucleoplasm Cytoplasm Cytosol Rab-protein Geranylgeranyltransferase Complex
	Molecular Function	GTPase Activity Protein Binding GTP Binding Cadherin Binding	GDP-dissociation Inhibitor Activity GTPase Activator Activity Small GTPase Binding
	Biological Process	Autophagosome Assembly Intracellular Protein Transport Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Endocytosis Autophagy Golgi Organization Vesicle-mediated Transport Cell Migration Virion Assembly Growth Hormone Secretion Melanosome Transport Interleukin-8 Production Substrate Adhesion-dependent Cell Spreading Defense Response To Bacterium Post-translational Protein Modification Vesicle Transport Along Microtubule COPII Vesicle Coating Cilium Assembly COPII-coated Vesicle Cargo Loading Establishment Of Endothelial Intestinal Barrier Positive Regulation Of Glycoprotein Metabolic Process Positive Regulation Of Ubiquitin Protein Ligase Activity	Intracellular Protein Transport Small GTPase Mediated Signal Transduction Vesicle-mediated Transport Protein Geranylgeranylation Positive Regulation Of GTPase Activity Post-translational Protein Modification
Pathways		Golgi Cisternae Pericentriolar Stack Reorganization Golgi Cisternae Pericentriolar Stack Reorganization COPII-mediated vesicle transport COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs	RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs
Drugs
Diseases
GWAS		High light scatter reticulocyte percentage of red cells ( 32888494) Reticulocyte count ( 32888494) Triglyceride levels ( 32154731)	Daytime sleep phenotypes ( 27126917)
Interacting Genes		28 interacting genes: ADCK1 CAPNS1 CDKN1A CHML CREB1 CSNK1D FSCN1 GOLGA2 GOLGA5 GORASP2 HIVEP1 MAPRE3 MICAL1 MICALL1 OCRL PSMD7 RABAC1 RABEP1 RABGGTA RABGGTB RABIF RFK RUSC2 SLC16A8 SYT5 TBC1D17 USO1 ZNF593	5 interacting genes: RAB1A RAB3A RAB5A RAB6A RABGGTB
Entrez ID		5861	1122
HPRD ID		01538	00341
Ensembl ID		ENSG00000138069	ENSG00000203668
Uniprot IDs		B7Z8M7 P62820 Q5U0I6	P26374
PDB IDs		2FOL 2WWX 3L0I 3SFV 3TKL 4FMB 4FMC 4FMD 4FME 4IRU 4JVS
Enriched GO Terms of Interacting Partners?
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