CHML and RAB3A

Data Source:
HPRD (two hybrid, in vitro)

		CHML	RAB3A
Description		CHM like Rab escort protein	RAB3A, member RAS oncogene family
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Rab-protein Geranylgeranyltransferase Complex	Acrosomal Vesicle Lysosome Endosome Cytosol Plasma Membrane Synaptic Vesicle Axon Secretory Granule Membrane Protein-containing Complex Terminal Bouton Perinuclear Region Of Cytoplasm Presynaptic Active Zone Clathrin-sculpted Acetylcholine Transport Vesicle Membrane Clathrin-sculpted Glutamate Transport Vesicle Membrane Clathrin-sculpted Gamma-aminobutyric Acid Transport Vesicle Membrane Clathrin-sculpted Monoamine Transport Vesicle Membrane Anchored Component Of Synaptic Vesicle Membrane Extracellular Vesicle
	Molecular Function	GDP-dissociation Inhibitor Activity GTPase Activator Activity Small GTPase Binding	ATPase Activator Activity GTPase Activity Protein Binding GTP Binding Protein C-terminus Binding GTP-dependent Protein Binding Myosin V Binding GDP-dissociation Inhibitor Binding ATPase Binding
	Biological Process	Intracellular Protein Transport Small GTPase Mediated Signal Transduction Vesicle-mediated Transport Protein Geranylgeranylation Positive Regulation Of GTPase Activity Post-translational Protein Modification	Plasma Membrane Repair Respiratory System Process Exocytosis Vesicle Docking Involved In Exocytosis Mitochondrion Organization Neurotransmitter Secretion Neuromuscular Synaptic Transmission Axonogenesis Protein Secretion Post-embryonic Development Regulation Of Synaptic Vesicle Priming Glutamate Secretion Regulation Of Dopamine Secretion Synaptic Vesicle Exocytosis Synaptic Vesicle Maturation Regulation Of Exocytosis Lung Development Regulation Of Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Lysosome Localization Positive Regulation Of ATPase Activity Synaptic Vesicle Recycling Neutrophil Degranulation Post-translational Protein Modification Constitutive Secretory Pathway Regulated Exocytosis Positive Regulation Of Exocytosis Regulation Of Short-term Neuronal Synaptic Plasticity Synaptic Vesicle Transport Maintenance Of Presynaptic Active Zone Structure Sensory Perception Of Touch Response To Electrical Stimulus Acrosomal Vesicle Exocytosis Evoked Neurotransmitter Secretion Protein Localization To Plasma Membrane Synaptic Vesicle Clustering Positive Regulation Of Regulated Secretory Pathway Regulation Of Plasma Membrane Repair Regulation Of Synaptic Vesicle Exocytosis
Pathways		RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs	Serotonin Neurotransmitter Release Cycle Norepinephrine Neurotransmitter Release Cycle Glutamate Neurotransmitter Release Cycle Dopamine Neurotransmitter Release Cycle Acetylcholine Neurotransmitter Release Cycle Neutrophil degranulation RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs GABA synthesis, release, reuptake and degradation
Drugs
Diseases
GWAS		Daytime sleep phenotypes ( 27126917)	Emphysema annual change measurement in smokers (percent low attenuation area) ( 31324189)
Interacting Genes		5 interacting genes: RAB1A RAB3A RAB5A RAB6A RABGGTB	29 interacting genes: A2M ADRB2 AP1M2 APP CASK CHM CHML CHRM4 DMXL2 ECSIT EGFR KRTAP10-8 MAST1 MYO5A PSEN1 RAB3IL1 RAB3IP RABAC1 RABGGTB RABIF RIMS1 RIMS2 RNF32 RPH3A RPH3AL SGSM2 SYTL4 SYTL5 VRTN
Entrez ID		1122	5864
HPRD ID		00341	01535
Ensembl ID		ENSG00000203668	ENSG00000105649
Uniprot IDs		P26374	A0A024R7I7 P20336
PDB IDs
Enriched GO Terms of Interacting Partners?
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