JAM2 and GPR20

Data Source:
BioGRID (two hybrid)

		JAM2	GPR20
Description		junctional adhesion molecule 2	G protein-coupled receptor 20
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Bicellular Tight Junction Cell Surface Somatodendritic Compartment Cell-cell Contact Zone Tight Junction Protein Complex Involved In Cell Adhesion	Cytosol Plasma Membrane Integral Component Of Plasma Membrane Receptor Complex
	Molecular Function	Integrin Binding Protein Binding	G Protein-coupled Receptor Activity
	Biological Process	Spermatid Development Myoblast Fusion Extracellular Matrix Organization Negative Regulation Of Myelination Maintenance Of Blood-brain Barrier Cellular Extravasation Leukocyte Migration Leukocyte Tethering Or Rolling Lymphocyte Aggregation Hematopoietic Stem Cell Migration To Bone Marrow Cell-cell Adhesion Positive Regulation Of Lymphocyte Migration	G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Rho Protein Signal Transduction Positive Regulation Of Cytosolic Calcium Ion Concentration Involved In Phospholipase C-activating G Protein-coupled Signaling Pathway
Pathways		Cell surface interactions at the vascular wall Integrin cell surface interactions	G alpha (s) signalling events ADORA2B mediated anti-inflammatory cytokines production
Drugs
Diseases
GWAS		Carboplatin disposition in epthelial ovarian cancer ( 29367611) Cognitive performance ( 19734545) Longitudinal change in brain amyloid plaque burden ( 26268530) Metabolite levels ( 23823483)	Bipolar disorder ( 21926972) Birth weight ( 31043758) Blood pressure traits (multi-trait analysis) ( 28498854) Diastolic blood pressure ( 27841878 27618447 28498854) Discordance in emotional problems in monozygotic twins ( 27043157) Height ( 31562340) Response to fenofibrate (total cholesterol levels) ( 27002377) Systolic blood pressure ( 27841878 27618447 28498854 31217584)
Interacting Genes		9 interacting genes: CSNK1A1L F2RL2 GPR20 JAM3 NME3 SOX8 TDP2 TJP1 YBX1	3 interacting genes: JAM2 POLR1H RPL31
Entrez ID		58494	2843
HPRD ID		06041	03550
Ensembl ID		ENSG00000154721	ENSG00000204882
Uniprot IDs		P57087	Q59GP3 Q99678
PDB IDs
Enriched GO Terms of Interacting Partners?
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