JAM2 and NME3

Data Source:
BioGRID (two hybrid)

		JAM2	NME3
Description		junctional adhesion molecule 2	NME/NM23 nucleoside diphosphate kinase 3
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Bicellular Tight Junction Cell Surface Somatodendritic Compartment Cell-cell Contact Zone Tight Junction Protein Complex Involved In Cell Adhesion	Cytosol
	Molecular Function	Integrin Binding Protein Binding	Nucleoside Diphosphate Kinase Activity Protein Binding ATP Binding Metal Ion Binding
	Biological Process	Spermatid Development Myoblast Fusion Extracellular Matrix Organization Negative Regulation Of Myelination Maintenance Of Blood-brain Barrier Cellular Extravasation Leukocyte Migration Leukocyte Tethering Or Rolling Lymphocyte Aggregation Hematopoietic Stem Cell Migration To Bone Marrow Cell-cell Adhesion Positive Regulation Of Lymphocyte Migration	Nucleoside Diphosphate Phosphorylation GTP Biosynthetic Process UTP Biosynthetic Process CTP Biosynthetic Process Apoptotic Process Nucleobase-containing Small Molecule Interconversion
Pathways		Cell surface interactions at the vascular wall Integrin cell surface interactions	Interconversion of nucleotide di- and triphosphates
Drugs
Diseases
GWAS		Carboplatin disposition in epthelial ovarian cancer ( 29367611) Cognitive performance ( 19734545) Longitudinal change in brain amyloid plaque burden ( 26268530) Metabolite levels ( 23823483)
Interacting Genes		9 interacting genes: CSNK1A1L F2RL2 GPR20 JAM3 NME3 SOX8 TDP2 TJP1 YBX1	11 interacting genes: APP DESI1 HTR2A JAM2 NME1 NME2 SGTA SGTB UBQLN1 UBQLN2 UBQLN4
Entrez ID		58494	4832
HPRD ID		06041	03488
Ensembl ID		ENSG00000154721	ENSG00000103024
Uniprot IDs		P57087	Q13232
PDB IDs			1ZS6
Enriched GO Terms of Interacting Partners?
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