GPR20 and POLR1H

Data Source:
BioGRID (two hybrid)

		GPR20	POLR1H
Description		G protein-coupled receptor 20	RNA polymerase I subunit H
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Plasma Membrane Integral Component Of Plasma Membrane Receptor Complex	Nucleoplasm RNA Polymerase I Complex
	Molecular Function	G Protein-coupled Receptor Activity	Nucleic Acid Binding DNA-directed 5'-3' RNA Polymerase Activity Protein Binding Zinc Ion Binding
	Biological Process	G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Rho Protein Signal Transduction Positive Regulation Of Cytosolic Calcium Ion Concentration Involved In Phospholipase C-activating G Protein-coupled Signaling Pathway	Nucleobase-containing Compound Metabolic Process Transcription Initiation From RNA Polymerase I Promoter Transcription Elongation From RNA Polymerase I Promoter Termination Of RNA Polymerase I Transcription MRNA Cleavage Positive Regulation Of Gene Expression, Epigenetic
Pathways		G alpha (s) signalling events ADORA2B mediated anti-inflammatory cytokines production	NoRC negatively regulates rRNA expression B-WICH complex positively regulates rRNA expression RNA Polymerase I Transcription Initiation RNA Polymerase I Transcription Initiation RNA Polymerase I Promoter Escape RNA Polymerase I Transcription Termination
Drugs
Diseases
GWAS		Bipolar disorder ( 21926972) Birth weight ( 31043758) Blood pressure traits (multi-trait analysis) ( 28498854) Diastolic blood pressure ( 27841878 27618447 28498854) Discordance in emotional problems in monozygotic twins ( 27043157) Height ( 31562340) Response to fenofibrate (total cholesterol levels) ( 27002377) Systolic blood pressure ( 27841878 27618447 28498854 31217584)
Interacting Genes		3 interacting genes: JAM2 POLR1H RPL31	18 interacting genes: APOA1 ATXN2 CIC DUSP1 FHL3 GFI1B GPR20 HAX1 IL15 IVNS1ABP MAPK8IP2 NONO SACS SERPINA3 TNS2 TRIML2 UBE2I ZNF593
Entrez ID		2843	30834
HPRD ID		03550	09601
Ensembl ID		ENSG00000204882	ENSG00000066379
Uniprot IDs		Q59GP3 Q99678	Q2L6J2 Q9P1U0
PDB IDs
Enriched GO Terms of Interacting Partners?
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