JAM2 and F2RL2

Data Source:
HPRD (in vivo, in vitro)

		JAM2	F2RL2
Description		junctional adhesion molecule 2	coagulation factor II thrombin receptor like 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Bicellular Tight Junction Cell Surface Somatodendritic Compartment Cell-cell Contact Zone Tight Junction Protein Complex Involved In Cell Adhesion	Extracellular Region Plasma Membrane Integral Component Of Plasma Membrane Apical Plasma Membrane Protein-containing Complex
	Molecular Function	Integrin Binding Protein Binding	Phosphatidylinositol Phospholipase C Activity G Protein-coupled Receptor Activity Protein Binding Thrombin-activated Receptor Activity
	Biological Process	Spermatid Development Myoblast Fusion Extracellular Matrix Organization Negative Regulation Of Myelination Maintenance Of Blood-brain Barrier Cellular Extravasation Leukocyte Migration Leukocyte Tethering Or Rolling Lymphocyte Aggregation Hematopoietic Stem Cell Migration To Bone Marrow Cell-cell Adhesion Positive Regulation Of Lymphocyte Migration	G Protein-coupled Receptor Signaling Pathway Blood Coagulation Response To Wounding Platelet Activation Positive Regulation Of Rho Protein Signal Transduction Positive Regulation Of Cytosolic Calcium Ion Concentration Involved In Phospholipase C-activating G Protein-coupled Signaling Pathway Thrombin-activated Receptor Signaling Pathway
Pathways		Cell surface interactions at the vascular wall Integrin cell surface interactions	Peptide ligand-binding receptors G alpha (q) signalling events Thrombin signalling through proteinase activated receptors (PARs) Thrombin signalling through proteinase activated receptors (PARs)
Drugs
Diseases
GWAS		Carboplatin disposition in epthelial ovarian cancer ( 29367611) Cognitive performance ( 19734545) Longitudinal change in brain amyloid plaque burden ( 26268530) Metabolite levels ( 23823483)	Mean platelet volume ( 28031487) Phenylephrine infusion rate during anesthesia ( 31455332)
Interacting Genes		9 interacting genes: CSNK1A1L F2RL2 GPR20 JAM3 NME3 SOX8 TDP2 TJP1 YBX1	8 interacting genes: CDH5 CTSG ECT2 F11R F2 F2RL3 JAM2 JAM3
Entrez ID		58494	2151
HPRD ID		06041	03561
Ensembl ID		ENSG00000154721	ENSG00000164220
Uniprot IDs		P57087	O00254
PDB IDs
Enriched GO Terms of Interacting Partners?
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