F2RL2 and JAM2

Data Source:
HPRD (in vivo, in vitro)

		F2RL2	JAM2
Description		coagulation factor II thrombin receptor like 2	junctional adhesion molecule 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Plasma Membrane Integral Component Of Plasma Membrane Apical Plasma Membrane Protein-containing Complex	Plasma Membrane Integral Component Of Plasma Membrane Bicellular Tight Junction Cell Surface Somatodendritic Compartment Cell-cell Contact Zone Tight Junction Protein Complex Involved In Cell Adhesion
	Molecular Function	Phosphatidylinositol Phospholipase C Activity G Protein-coupled Receptor Activity Protein Binding Thrombin-activated Receptor Activity	Integrin Binding Protein Binding
	Biological Process	G Protein-coupled Receptor Signaling Pathway Blood Coagulation Response To Wounding Platelet Activation Positive Regulation Of Rho Protein Signal Transduction Positive Regulation Of Cytosolic Calcium Ion Concentration Involved In Phospholipase C-activating G Protein-coupled Signaling Pathway Thrombin-activated Receptor Signaling Pathway	Spermatid Development Myoblast Fusion Extracellular Matrix Organization Negative Regulation Of Myelination Maintenance Of Blood-brain Barrier Cellular Extravasation Leukocyte Migration Leukocyte Tethering Or Rolling Lymphocyte Aggregation Hematopoietic Stem Cell Migration To Bone Marrow Cell-cell Adhesion Positive Regulation Of Lymphocyte Migration
Pathways		Peptide ligand-binding receptors G alpha (q) signalling events Thrombin signalling through proteinase activated receptors (PARs) Thrombin signalling through proteinase activated receptors (PARs)	Cell surface interactions at the vascular wall Integrin cell surface interactions
Drugs
Diseases
GWAS		Mean platelet volume ( 28031487) Phenylephrine infusion rate during anesthesia ( 31455332)	Carboplatin disposition in epthelial ovarian cancer ( 29367611) Cognitive performance ( 19734545) Longitudinal change in brain amyloid plaque burden ( 26268530) Metabolite levels ( 23823483)
Interacting Genes		8 interacting genes: CDH5 CTSG ECT2 F11R F2 F2RL3 JAM2 JAM3	9 interacting genes: CSNK1A1L F2RL2 GPR20 JAM3 NME3 SOX8 TDP2 TJP1 YBX1
Entrez ID		2151	58494
HPRD ID		03561	06041
Ensembl ID		ENSG00000164220	ENSG00000154721
Uniprot IDs		O00254	P57087
PDB IDs
Enriched GO Terms of Interacting Partners?
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