PLEKHB1 and CCR8

Data Source:
BioGRID (two hybrid)

		PLEKHB1	CCR8
Description		pleckstrin homology domain containing B1	C-C motif chemokine receptor 8
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Integral Component Of Membrane	Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane
	Molecular Function	Protein Binding	Chemokine Receptor Activity Coreceptor Activity C-C Chemokine Receptor Activity C-C Chemokine Binding
	Biological Process	Multicellular Organism Development Phototransduction Regulation Of Cell Differentiation	Chemotaxis Immune Response Cell Adhesion G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Calcium-mediated Signaling Cell Chemotaxis Chemokine-mediated Signaling Pathway
Pathways			Chemokine receptors bind chemokines G alpha (i) signalling events
Drugs
Diseases
GWAS		Dimensional psychopathology (Cognitive) ( 29496196) Glucose homeostasis traits ( 25524916) Hand grip strength ( 27325353) Smoking status (ever vs never smokers) ( 30643258)	Daytime sleep phenotypes ( 27126917) Medication use (thyroid preparations) ( 31015401)
Interacting Genes		13 interacting genes: ACVR1 ATXN1 BAG3 BMPR1B C10orf55 CCR8 GLIS2 GNGT1 RAP1GDS1 SMAD1 TGFBR1 VENTX ZDHHC17	19 interacting genes: ATP2A1 CCL1 CCL16 CCL17 CCL4 EI24 ERGIC3 GABBR1 GABRD NAGPA PAQR6 PLEKHB1 RTN3 SPNS1 SPP1 THY1 TPST1 TPST2 UCKL1
Entrez ID		58473	1237
HPRD ID		09630	03497
Ensembl ID		ENSG00000021300	ENSG00000179934
Uniprot IDs		A0A024R5H7 A0A024R5H9 A0A024R5J2 Q9UF11	P51685
PDB IDs
Enriched GO Terms of Interacting Partners?
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