HSCB and BBS1

Data Source:
BioGRID (two hybrid)

		HSCB	BBS1
Description		HscB mitochondrial iron-sulfur cluster cochaperone	Bardet-Biedl syndrome 1
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GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Mitochondrion Cytosol	Centrosome Cytosol Axoneme BBSome Ciliary Basal Body Ciliary Membrane
	Molecular Function	ATPase Activator Activity Molecular_function Protein Binding Identical Protein Binding Metal Ion Binding Chaperone Binding	RNA Polymerase II Repressing Transcription Factor Binding Patched Binding Smoothened Binding Protein Binding
	Biological Process	Iron-sulfur Cluster Assembly Positive Regulation Of ATPase Activity [2Fe-2S] Cluster Assembly Protein Complex Oligomerization Protein Maturation By Iron-sulfur Cluster Transfer	Visual Perception Sensory Perception Of Smell Golgi To Plasma Membrane Protein Transport Photoreceptor Cell Maintenance Response To Stimulus Cilium Assembly Protein Localization To Cilium Non-motile Cilium Assembly
Pathways		Mitochondrial protein import Mitochondrial protein import Mitochondrial iron-sulfur cluster biogenesis	BBSome-mediated cargo-targeting to cilium
Drugs
Diseases			Bardet-Biedl syndrome (BBS)
GWAS		Breast size ( 27182965) Diastolic blood pressure ( 27841878) Esophageal cancer and gastric cancer ( 20729852) Mean platelet volume ( 32888494) Myeloproliferative neoplasms ( 33057200) Pancreatic cancer ( 25086665) Red cell distribution width ( 27863252) Systolic blood pressure ( 27841878)	Bipolar disorder ( 21926972) Height ( 28552196)
Interacting Genes		4 interacting genes: AGTRAP BBS1 BBS2 BBS4	13 interacting genes: BHMT CALCA DCTN1 EEF1A1 EIF3A EPAS1 EXOC7 FHOD1 HSCB KRT18 PARK7 PAX2 TSPAN7
Entrez ID		150274	582
HPRD ID		16289	01950
Ensembl ID		ENSG00000100209	ENSG00000174483
Uniprot IDs		A0A384NYJ4 B0QYH2 Q8IWL3	Q8NFJ9
PDB IDs		3BVO	6XT9
Enriched GO Terms of Interacting Partners?
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