RAP2C and RAP1GDS1

Data Source:
BioGRID (two hybrid)

		RAP2C	RAP1GDS1
Description		RAP2C, member of RAS oncogene family	Rap1 GTPase-GDP dissociation stimulator 1
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Plasma Membrane Bicellular Tight Junction Cell-cell Contact Zone Recycling Endosome Membrane Extracellular Exosome Tertiary Granule Membrane	Mitochondrion Endoplasmic Reticulum Cytosol Extracellular Exosome
	Molecular Function	Transcription Coactivator Activity GTPase Activity Protein Binding GTP Binding GDP Binding	GTPase Activator Activity Protein Binding
	Biological Process	Microvillus Assembly Negative Regulation Of Cell Migration Positive Regulation Of Protein Autophosphorylation Rap Protein Signal Transduction Neutrophil Degranulation Positive Regulation Of Transcription, DNA-templated Regulation Of Protein Tyrosine Kinase Activity Establishment Of Endothelial Intestinal Barrier	Vascular Associated Smooth Muscle Contraction Myosin Filament Assembly Negative Regulation Of Endoplasmic Reticulum Calcium Ion Concentration Positive Regulation Of GTPase Activity Positive Regulation Of Mitochondrial Calcium Ion Concentration
Pathways		Neutrophil degranulation
Drugs
Diseases
GWAS		Gestational age at birth (maternal effect) ( 28877031) Uterine fibroids ( 31649266)	Biochemical measures ( 19260141) Response to fenofibrate (total cholesterol levels) ( 27002377)
Interacting Genes		2 interacting genes: ADRB2 RAP1GDS1	23 interacting genes: CDC42 DIRAS1 DIRAS2 DOC2A EGFR HRAS KIFAP3 KRAS MBIP NRAS PLEKHB1 PTPRF PUF60 RAB6B RAC1 RAP1A RAP2B RAP2C RHOA RNF19B RRAS RRAS2 ZNF451
Entrez ID		57826	5910
HPRD ID		06706	11763
Ensembl ID		ENSG00000123728	ENSG00000138698
Uniprot IDs		A0A087X2C3 Q9Y3L5	B3KNU0 P52306 Q6U7G8
PDB IDs			5XGC 5ZHX
Enriched GO Terms of Interacting Partners?
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