KLHL8 and RLBP1

Data Source:
BioGRID (two hybrid)

		KLHL8	RLBP1
Description		kelch like family member 8	retinaldehyde binding protein 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cul3-RING Ubiquitin Ligase Complex	Nucleoplasm Centrosome Cytosol Cell Body
	Molecular Function		11-cis Retinal Binding Protein Binding Retinol Binding Phosphatidylinositol Bisphosphate Binding
	Biological Process	Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination	Retinoid Metabolic Process Vitamin A Metabolic Process Visual Perception Response To Stimulus
Pathways			The retinoid cycle in cones (daylight vision) The retinoid cycle in cones (daylight vision) Retinoid cycle disease events The canonical retinoid cycle in rods (twilight vision)
Drugs
Diseases			Newfoundland rod-cone dystrophy (NFRCD) Familial flecked retina syndrome, including: Doyne honeycomb degeneration of retina (DHRD); Basal laminar drusen (BLD); Fundus albipunctatus (FA); Retinitis punctata albescens (RPA); Bietti crystalline corneoretinal dystrophy (BCD)
GWAS		Alanine transaminase levels ( 29403010) Aspartate aminotransferase levels ( 29403010) Bulimia nervosa ( 23568457) Eyebrow thickness ( 26926045) HDL cholesterol levels ( 28334899) Rosacea symptom severity ( 29771307) Total cholesterol levels ( 30275531) Triglyceride levels ( 28334899 29403010) Triglycerides ( 24097068 25961943 20686565)	Advanced age-related macular degeneration ( 28813576) Age-related macular degeneration (SNP x mitochondrial G12771A interaction) ( 28813576) Schizophrenia ( 28991256)
Interacting Genes		13 interacting genes: ARMC9 ATXN1 CA8 COIL MAPK9 PNMT PPM1F RAPSN RLBP1 SULT2B1 TEX101 TP53I13 USP7	4 interacting genes: APP KLHL8 RDH5 SLC9A3R1
Entrez ID		57563	6017
HPRD ID		13928	01572
Ensembl ID		ENSG00000145332	ENSG00000140522
Uniprot IDs		B3KY78 Q68DU9 Q7Z330 Q9P2G9	P12271
PDB IDs			1XGG 1XGH 3HX3 3HY5 4CIZ 4CJ6
Enriched GO Terms of Interacting Partners?
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