KLHL8 and COIL

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		KLHL8	COIL
Description		kelch like family member 8	coilin
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cul3-RING Ubiquitin Ligase Complex	Fibrillar Center Nucleus Nucleoplasm Nucleolus Cajal Body Membrane Nuclear Body
	Molecular Function		Protein Binding Protein C-terminus Binding U1 SnRNA Binding U2 SnRNA Binding Identical Protein Binding
	Biological Process	Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination	Spliceosomal SnRNP Assembly
Pathways
Drugs
Diseases
GWAS		Alanine transaminase levels ( 29403010) Aspartate aminotransferase levels ( 29403010) Bulimia nervosa ( 23568457) Eyebrow thickness ( 26926045) HDL cholesterol levels ( 28334899) Rosacea symptom severity ( 29771307) Total cholesterol levels ( 30275531) Triglyceride levels ( 28334899 29403010) Triglycerides ( 24097068 25961943 20686565)	Height ( 18391951)
Interacting Genes		13 interacting genes: ARMC9 ATXN1 CA8 COIL MAPK9 PNMT PPM1F RAPSN RLBP1 SULT2B1 TEX101 TP53I13 USP7	83 interacting genes: ACTN1 ACTN2 ACTN4 ADAMTS12 APP ARMCX1 ATXN1 ATXN1L BYSL C1QBP C9orf72 CCDC136 CCDC159 CCDC57 CCNE1 CDC23 CDK2 CEP70 CEP76 CSNK2B CYB5R2 DHX16 DNAJA3 DRG1 DYNC2I2 ELOA2 FGF12 FHL5 FXR2 GCC1 HSF2BP KALRN KAZN KDM1A KLC2 KLC4 KLHL42 KLHL8 KPNA3 LNX1 MAD1L1 MCRS1 MFAP1 MYO15B MYO5B NFU1 NIF3L1 NKAPD1 NOLC1 NTAQ1 NUDT18 PDE4D PDLIM5 PIAS4 PICK1 PLEKHG4 PLOD3 POLR2L POLR3C PREPL PRMT1 PRMT8 PSMA1 PSME3 PTS SART3 SCYL1 SMN1 SNRPB SNRPF SNX6 SPANXN2 SRPK2 TAF9 TCAF1 TFCP2 TGS1 TSPYL2 XRCC5 XRCC6 ZBTB25 ZCCHC10 ZNF277
Entrez ID		57563	8161
HPRD ID		13928	02605
Ensembl ID		ENSG00000145332	ENSG00000121058
Uniprot IDs		B3KY78 Q68DU9 Q7Z330 Q9P2G9	P38432
PDB IDs
Enriched GO Terms of Interacting Partners?
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