RLBP1 and RDH5

Data Source:
BioGRID (pull down)
HPRD (in vitro)

		RLBP1	RDH5
Description		retinaldehyde binding protein 1	retinol dehydrogenase 5
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Centrosome Cytosol Cell Body	Endoplasmic Reticulum Lumen Endoplasmic Reticulum Membrane Integral Component Of Membrane Cell Body
	Molecular Function	11-cis Retinal Binding Protein Binding Retinol Binding Phosphatidylinositol Bisphosphate Binding	Retinol Dehydrogenase Activity Protein Homodimerization Activity Androsterone Dehydrogenase Activity Androstan-3-alpha,17-beta-diol Dehydrogenase Activity
	Biological Process	Retinoid Metabolic Process Vitamin A Metabolic Process Visual Perception Response To Stimulus	Retinoid Metabolic Process Visual Perception Steroid Metabolic Process Retinol Metabolic Process Response To Stimulus
Pathways		The retinoid cycle in cones (daylight vision) The retinoid cycle in cones (daylight vision) Retinoid cycle disease events The canonical retinoid cycle in rods (twilight vision)	Retinoid cycle disease events The canonical retinoid cycle in rods (twilight vision) RA biosynthesis pathway
Drugs			NADH Vitamin A
Diseases		Newfoundland rod-cone dystrophy (NFRCD) Familial flecked retina syndrome, including: Doyne honeycomb degeneration of retina (DHRD); Basal laminar drusen (BLD); Fundus albipunctatus (FA); Retinitis punctata albescens (RPA); Bietti crystalline corneoretinal dystrophy (BCD)	Familial flecked retina syndrome, including: Doyne honeycomb degeneration of retina (DHRD); Basal laminar drusen (BLD); Fundus albipunctatus (FA); Retinitis punctata albescens (RPA); Bietti crystalline corneoretinal dystrophy (BCD)
GWAS		Advanced age-related macular degeneration ( 28813576) Age-related macular degeneration (SNP x mitochondrial G12771A interaction) ( 28813576) Schizophrenia ( 28991256)	Advanced age-related macular degeneration ( 26691988) High myopia ( 31816047) Macular thickness ( 30535121) Myopia ( 27182965) Refractive error ( 23396134) Spherical equivalent (joint analysis main effects and education interaction) ( 27020472) Spherical equivalent or myopia (age of diagnosis) ( 29808027)
Interacting Genes		4 interacting genes: APP KLHL8 RDH5 SLC9A3R1	3 interacting genes: ORC4 RGR RLBP1
Entrez ID		6017	5959
HPRD ID		01572	03370
Ensembl ID		ENSG00000140522	ENSG00000135437
Uniprot IDs		P12271	A0A024RB18 Q92781
PDB IDs		1XGG 1XGH 3HX3 3HY5 4CIZ 4CJ6
Enriched GO Terms of Interacting Partners?
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