TTYH1 and USP54

Data Source:
BioGRID (affinity chromatography technology)

		TTYH1	USP54
Description		tweety family member 1	ubiquitin specific peptidase 54
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane Smooth Endoplasmic Reticulum Membrane Filopodium Membrane Filopodium Tip Chloride Channel Complex Synapse
	Molecular Function	Intracellular Calcium Activated Chloride Channel Activity Chloride Channel Activity Iron Ion Transmembrane Transporter Activity Calcium Ion Binding Protein Binding Volume-sensitive Chloride Channel Activity	Thiol-dependent Ubiquitin-specific Protease Activity Protein Binding
	Biological Process	Mitotic Cell Cycle Chloride Transport Iron Ion Transport Cell-substrate Adhesion Ion Transmembrane Transport Iron Ion Transmembrane Transport Filopodium Assembly Cell-cell Adhesion Chloride Transmembrane Transport	Protein Deubiquitination Protein Phosphopantetheinylation
Pathways
Drugs
Diseases
GWAS		Blood trace element (Se levels) ( 23720494) Idiopathic pulmonary fibrosis ( 29066090)	Childhood ALL/LBL (acute lymphoblastic leukemia/lymphoblastic lymphoma) treatment-related venous thromboembolism ( 32438682) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223)
Interacting Genes		5 interacting genes: CCR9 DRD2 GPR37 HTR6 TMEM60	88 interacting genes: ANKRD11 ANKS1A ARMC7 ATN1 ATXN1 ATXN1L ATXN7L2 BFSP2 BHLHE40 CARD10 CCDC13 CCDC24 CCNK CDC23 CHCHD2 CHERP CHMP1B CHMP2A CHMP2B CHMP4C CSTF2 CYSRT1 DMRT3 DOK6 DTX2 EIF4E2 EPM2AIP1 EXOC8 FAM124B FBXO17 FNDC3B FOXI1 GCM2 HGS HNF1B HNRNPF HOXC8 IGFN1 INSC KCTD9 LMO3 LNX1 MED25 MID2 NUDT22 NXT2 OIP5 OTX1 PCSK5 PHF1 PLA2G6 PLAC8 PLEKHN1 POLR1C PRDM6 PRKAB2 PRR35 QRICH1 RACK1 RAMAC RBPMS2 RHOBTB3 RNF208 SEC24A SHARPIN SHC3 SMARCD1 SMYD1 SNRPB SS18L1 STK16 TBX6 TCEA2 TEKT5 TENT5B TFAP2D TLE5 TNS2 TOLLIP TSEN15 TSSK3 TTC19 UBC USP2 VENTX ZCCHC14 ZNF148 ZNF76
Entrez ID		57348	159195
HPRD ID		12043	15641
Ensembl ID		ENSG00000167614	ENSG00000166348
Uniprot IDs		Q9H313	B7Z7X1 Q70EL1
PDB IDs
Enriched GO Terms of Interacting Partners?
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