PTGDS and HK2

Data Source:
HPRD (two hybrid, in vivo, in vitro)

		PTGDS	HK2
Description		prostaglandin D2 synthase	hexokinase 2
Image
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Endoplasmic Reticulum Membrane Rough Endoplasmic Reticulum Golgi Apparatus Nuclear Membrane Perinuclear Region Of Cytoplasm Extracellular Exosome	Mitochondrion Mitochondrial Outer Membrane Centrosome Cytosol Plasma Membrane Membrane Sarcoplasmic Reticulum Intracellular Membrane-bounded Organelle
	Molecular Function	Prostaglandin-D Synthase Activity Retinoid Binding Fatty Acid Binding Protein Binding Small Molecule Binding	Glucokinase Activity Hexokinase Activity Protein Binding ATP Binding Glucose Binding Fructokinase Activity Mannokinase Activity
	Biological Process	Prostaglandin Biosynthetic Process Cyclooxygenase Pathway Mast Cell Degranulation Regulation Of Circadian Sleep/wake Cycle, Sleep	Response To Hypoxia Cellular Glucose Homeostasis Response To Ischemia Fructose 6-phosphate Metabolic Process Glycolytic Process Lactation Apoptotic Mitochondrial Changes Negative Regulation Of Mitochondrial Membrane Permeability Positive Regulation Of Angiogenesis Regulation Of Glucose Import Carbohydrate Phosphorylation Glucose 6-phosphate Metabolic Process Canonical Glycolysis Establishment Of Protein Localization To Mitochondrion Maintenance Of Protein Location In Mitochondrion Positive Regulation Of Autophagy Of Mitochondrion In Response To Mitochondrial Depolarization Cellular Response To Leukemia Inhibitory Factor Negative Regulation Of Reactive Oxygen Species Metabolic Process
Pathways		Synthesis of Prostaglandins (PG) and Thromboxanes (TX) Transcriptional regulation of testis differentiation	Glycolysis
Drugs		Vitamin A
Diseases
GWAS		Beta-trace protein levels ( 23328707) Blood protein levels ( 29875488) Corneal structure ( 23291589)	Femoral neck bone geometry ( 22087292)
Interacting Genes		22 interacting genes: ADRB2 AKT1 ARRB2 ATXN1 BCAT2 CACNA1A CAPN1 CARD10 CYSRT1 EGFR HK2 HK3 HSP90AA1 KRTAP10-3 KRTAP10-7 KRTAP12-3 MLH1 PTGER1 PTGER2 PTGFR SHBG UBQLN2	9 interacting genes: ENO1 MAGEA12 PRKCE PTGDS SLC2A4 SUMO2 UBQLN1 UBQLN4 ZBTB17
Entrez ID		5730	3099
HPRD ID		08904	03080
Ensembl ID		ENSG00000107317	ENSG00000159399
Uniprot IDs		A0A024R8G3 P41222	P52789
PDB IDs		2WWP 3O19 3O22 3O2Y 4IMN 4IMO 4ORR 4ORS 4ORU 4ORW 4ORX 4ORY 4OS0 4OS3 4OS8 5WY9	2NZT 5HEX 5HFU 5HG1
Enriched GO Terms of Interacting Partners?
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