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PTGDS

Description prostaglandin D2 synthase
Image
GO Annotations Cellular Component
  • Extracellular Region
  • Extracellular Space
  • Endoplasmic Reticulum Membrane
  • Rough Endoplasmic Reticulum
  • Golgi Apparatus
  • Nuclear Membrane
  • Perinuclear Region Of Cytoplasm
  • Extracellular Exosome
Molecular Function
  • Prostaglandin-D Synthase Activity
  • Retinoid Binding
  • Fatty Acid Binding
  • Protein Binding
  • Small Molecule Binding
Biological Process
  • Prostaglandin Biosynthetic Process
  • Cyclooxygenase Pathway
  • Mast Cell Degranulation
  • Regulation Of Circadian Sleep/wake Cycle, Sleep
Pathways
  • Synthesis of Prostaglandins (PG) and Thromboxanes (TX)
  • Transcriptional regulation of testis differentiation
Drugs
  • Vitamin A
Diseases
GWAS
  • Beta-trace protein levels ( 23328707)
  • Blood protein levels ( 29875488)
  • Corneal structure ( 23291589)
Interacting Genes 22 interacting genes: ADRB2 AKT1 ARRB2 ATXN1 BCAT2 CACNA1A CAPN1 CARD10 CYSRT1 EGFR HK2 HK3 HSP90AA1 KRTAP10-3 KRTAP10-7 KRTAP12-3 MLH1 PTGER1 PTGER2 PTGFR SHBG UBQLN2
Entrez ID 5730
HPRD ID 08904
Ensembl ID ENSG00000107317
Uniprot IDs A0A024R8G3 P41222
PDB IDs 2WWP 3O19 3O22 3O2Y 4IMN 4IMO 4ORR 4ORS 4ORU 4ORW 4ORX 4ORY 4OS0 4OS3 4OS8 5WY9
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025